Hybrid additive-subtractive laser fabrication platform for shaping hydrogels

Pranav Soman, Puskal Kunwar, Zheng Xiong, Yin Zhu, Haiyan Li, Alex Filip, Rafael Ramos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Statement of Purpose. Sculpting and shaping hydrogels into complex multiscale functional devices remains challenging [1]. In recent years, additive fabrication methods have been used to print hydrogel constructs, however creating multiscale hydrogel-based devices with three dimensional (3D) internal features remains difficult. Ultrafast lasers have revolutionized the processing of hydrogels due to its unique property of nonlinear multiphoton absorption [2]. Although ultrafast lasers have been used in both additive crosslinking and subtractive ablation modes, efforts to combine these two well established methods into a single versatile manufacturing platform have been difficult due to (i) material incompatibilities and/or significant differences in laser processing requirements of the two processes, (ii) use of photoresist that are not compatible with living cells or mechanically weak and difficult-to-print biomimetic hydrogels, (iii) limited scalability in the z-direction due to low laser penetration depth, associated with the optical absorption/scattering properties of hydrogels [3]. In this work, we report the design and development of a new hybrid laser printing (HLP) method that allows processing of multiscale hydrogel-based constructs that cannot be fabricated with existing techniques and potentially enable new research applications in biomedical sciences.

Original languageEnglish (US)
Title of host publicationSociety for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publicationThe Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
PublisherSociety for Biomaterials
Number of pages1
ISBN (Electronic)9781510883901
StatePublished - Jan 1 2019
Event42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States
Duration: Apr 3 2019Apr 6 2019

Publication series

NameTransactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume40
ISSN (Print)1526-7547

Conference

Conference42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
CountryUnited States
CitySeattle
Period4/3/194/6/19

Fingerprint

Hydrogels
Hydrogel
Lasers
Fabrication
Ultrafast lasers
Processing
Biomimetics
Photoresists
Ablation
Equipment and Supplies
Printing
Crosslinking
Light absorption
Scalability
Cells
Scattering
Research

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Biotechnology
  • Biomaterials
  • Materials Chemistry

Cite this

Soman, P., Kunwar, P., Xiong, Z., Zhu, Y., Li, H., Filip, A., & Ramos, R. (2019). Hybrid additive-subtractive laser fabrication platform for shaping hydrogels. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40). Society for Biomaterials.

Hybrid additive-subtractive laser fabrication platform for shaping hydrogels. / Soman, Pranav; Kunwar, Puskal; Xiong, Zheng; Zhu, Yin; Li, Haiyan; Filip, Alex; Ramos, Rafael.

Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Soman, P, Kunwar, P, Xiong, Z, Zhu, Y, Li, H, Filip, A & Ramos, R 2019, Hybrid additive-subtractive laser fabrication platform for shaping hydrogels. in Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, vol. 40, Society for Biomaterials, 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence, Seattle, United States, 4/3/19.
Soman P, Kunwar P, Xiong Z, Zhu Y, Li H, Filip A et al. Hybrid additive-subtractive laser fabrication platform for shaping hydrogels. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials. 2019. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).
Soman, Pranav ; Kunwar, Puskal ; Xiong, Zheng ; Zhu, Yin ; Li, Haiyan ; Filip, Alex ; Ramos, Rafael. / Hybrid additive-subtractive laser fabrication platform for shaping hydrogels. Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).
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