Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables

Wen Wang, Lining Yao, Chin Yi Cheng, Teng Zhang, Hiroshi Atsumi, Luda Wang, Guanyun Wang, Oksana Anilionyte, Helene Steiner, Jifei Ou, Kang Zhou, Chris Wawrousek, Katherine Petrecca, Angela M. Belcher, Rohit Karnik, Xuanhe Zhao, Daniel I.C. Wang, Hiroshi Ishii

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

Cells' biomechanical responses to external stimuli have been intensively studied but rarely implemented into devices that interact with the human body. We demonstrate that the hygroscopic and biofluorescent behaviors of living cells can be engineered to design biohybrid wearables, which give multifunctional responsiveness to human sweat. By depositing genetically tractable microbes on a humidity-inert material to form a heterogeneous multilayered structure, we obtained biohybrid films that can reversibly change shape and biofluorescence intensity within a few seconds in response to environmental humidity gradients. Experimental characterization and mechanical modeling of the film were performed to guide the design of a wearable running suit and a fluorescent shoe prototype with bio-flaps that dynamically modulates ventilation in synergy with the body's need for cooling.

Original languageEnglish (US)
Article numbere1601984
JournalScience Advances
Volume3
Issue number5
DOIs
StatePublished - May 2017

ASJC Scopus subject areas

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    Wang, W., Yao, L., Cheng, C. Y., Zhang, T., Atsumi, H., Wang, L., Wang, G., Anilionyte, O., Steiner, H., Ou, J., Zhou, K., Wawrousek, C., Petrecca, K., Belcher, A. M., Karnik, R., Zhao, X., Wang, D. I. C., & Ishii, H. (2017). Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables. Science Advances, 3(5), [e1601984]. https://doi.org/10.1126/sciadv.1601984