Glucose enhancement of performance of memory tests in young and aged humans

J. L. Hall; L. A. Gonder-Frederick; W. W. Chewning; J. Silveira; P. E. Gold

doi:10.1016/0028-3932(89)90096-1

Glucose enhancement of performance of memory tests in young and aged humans

J. L. Hall, L. A. Gonder-Frederick, W. W. Chewning, J. Silveira, P. E. Gold

Research output: Contribution to journal › Article › peer-review

211 Scopus citations

Abstract

Recent findings indicate that glucose administration enhances memory processes in rodents. This study examined the effects of glucose on memory in humans. After drinking glucose- or saccharin-flavored beverages, college-aged and elderly humans were tested with modified versions of the Wechsler Memory Scale. Beverages and tests were administered in a counter-balanced, crossover design, enabling within subject comparisons. The major findings were: (1) glucose enhanced memory in elderly and, to a lesser extent, in young subjects; and (2) glucose tolerance in individual subjects predicted memory in elderly, but not in young subjects on both glucose and saccharin test days.

Original language	English (US)
Pages (from-to)	1129-1138
Number of pages	10
Journal	Neuropsychologia
Volume	27
Issue number	9
DOIs	https://doi.org/10.1016/0028-3932(89)90096-1
State	Published - 1989
Externally published	Yes

ASJC Scopus subject areas

Experimental and Cognitive Psychology
Cognitive Neuroscience
Behavioral Neuroscience

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title = "Glucose enhancement of performance of memory tests in young and aged humans",

abstract = "Recent findings indicate that glucose administration enhances memory processes in rodents. This study examined the effects of glucose on memory in humans. After drinking glucose- or saccharin-flavored beverages, college-aged and elderly humans were tested with modified versions of the Wechsler Memory Scale. Beverages and tests were administered in a counter-balanced, crossover design, enabling within subject comparisons. The major findings were: (1) glucose enhanced memory in elderly and, to a lesser extent, in young subjects; and (2) glucose tolerance in individual subjects predicted memory in elderly, but not in young subjects on both glucose and saccharin test days.",

author = "Hall, {J. L.} and Gonder-Frederick, {L. A.} and Chewning, {W. W.} and J. Silveira and Gold, {P. E.}",

note = "Funding Information: *Supported by research grants from the National Institute of Mental Health (MH 31141). the Office of Naval Research (N00014-85K0472), the National Institute ofHealth (07320). the American Diabetes Association. and the Virginia Diabetes Association. IlCorrespondence to be addressed to: Jeremy L. Hall, Department of Psychology. University of Virginia. Chzrlottesville, VA 22903, U.S.A. $To whom reprint requests should be addressed.",

year = "1989",

doi = "10.1016/0028-3932(89)90096-1",

language = "English (US)",

volume = "27",

pages = "1129--1138",

journal = "Neuropsychologia",

issn = "0028-3932",

publisher = "Elsevier",

number = "9",

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TY - JOUR

T1 - Glucose enhancement of performance of memory tests in young and aged humans

AU - Hall, J. L.

AU - Gonder-Frederick, L. A.

AU - Chewning, W. W.

AU - Silveira, J.

AU - Gold, P. E.

N1 - Funding Information: *Supported by research grants from the National Institute of Mental Health (MH 31141). the Office of Naval Research (N00014-85K0472), the National Institute ofHealth (07320). the American Diabetes Association. and the Virginia Diabetes Association. IlCorrespondence to be addressed to: Jeremy L. Hall, Department of Psychology. University of Virginia. Chzrlottesville, VA 22903, U.S.A. $To whom reprint requests should be addressed.

PY - 1989

Y1 - 1989

N2 - Recent findings indicate that glucose administration enhances memory processes in rodents. This study examined the effects of glucose on memory in humans. After drinking glucose- or saccharin-flavored beverages, college-aged and elderly humans were tested with modified versions of the Wechsler Memory Scale. Beverages and tests were administered in a counter-balanced, crossover design, enabling within subject comparisons. The major findings were: (1) glucose enhanced memory in elderly and, to a lesser extent, in young subjects; and (2) glucose tolerance in individual subjects predicted memory in elderly, but not in young subjects on both glucose and saccharin test days.

AB - Recent findings indicate that glucose administration enhances memory processes in rodents. This study examined the effects of glucose on memory in humans. After drinking glucose- or saccharin-flavored beverages, college-aged and elderly humans were tested with modified versions of the Wechsler Memory Scale. Beverages and tests were administered in a counter-balanced, crossover design, enabling within subject comparisons. The major findings were: (1) glucose enhanced memory in elderly and, to a lesser extent, in young subjects; and (2) glucose tolerance in individual subjects predicted memory in elderly, but not in young subjects on both glucose and saccharin test days.

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Glucose enhancement of performance of memory tests in young and aged humans

Abstract

ASJC Scopus subject areas

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