Glucose enhancement of performance of memory tests in young and aged humans

J. L. Hall, L. A. Gonder-Frederick, W. W. Chewning, J. Silveira, P. E. Gold

Research output: Contribution to journalArticlepeer-review

201 Scopus citations

Abstract

Recent findings indicate that glucose administration enhances memory processes in rodents. This study examined the effects of glucose on memory in humans. After drinking glucose- or saccharin-flavored beverages, college-aged and elderly humans were tested with modified versions of the Wechsler Memory Scale. Beverages and tests were administered in a counter-balanced, crossover design, enabling within subject comparisons. The major findings were: (1) glucose enhanced memory in elderly and, to a lesser extent, in young subjects; and (2) glucose tolerance in individual subjects predicted memory in elderly, but not in young subjects on both glucose and saccharin test days.

Original languageEnglish (US)
Pages (from-to)1129-1138
Number of pages10
JournalNeuropsychologia
Volume27
Issue number9
DOIs
StatePublished - 1989
Externally publishedYes

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

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