Glucose enhancement of performance of memory tests in young and aged humans

J. L. Hall, L. A. Gonder-Frederick, W. W. Chewning, J. Silveira, Paul Ernest Gold

Research output: Contribution to journalArticle

199 Scopus citations


Recent findings indicate that glucose administration enhances memory processes in rodents. This study examined the effects of glucose on memory in humans. After drinking glucose- or saccharin-flavored beverages, college-aged and elderly humans were tested with modified versions of the Wechsler Memory Scale. Beverages and tests were administered in a counter-balanced, crossover design, enabling within subject comparisons. The major findings were: (1) glucose enhanced memory in elderly and, to a lesser extent, in young subjects; and (2) glucose tolerance in individual subjects predicted memory in elderly, but not in young subjects on both glucose and saccharin test days.

Original languageEnglish (US)
Pages (from-to)1129-1138
Number of pages10
Issue number9
StatePublished - 1989
Externally publishedYes


ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Neuropsychology and Physiological Psychology

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