TY - JOUR
T1 - Germline cysts
T2 - A conserved phase of germ cell development?
AU - Pepling, Melissa E.
AU - De Cuevas, Margaret
AU - Sprading, Allan C.
PY - 1999/7/1
Y1 - 1999/7/1
N2 - Germ cells in many vertebrate and invertebrate species initiate gametogenesis by forming groups of interconnected cells known as germline cysts. Recent studies using Xenopus, mouse and Drosophila are beginning to uncover the cellular and molecular mechanisms that control germline cyst formation and, in conjunction with morphological evidence, suggest that the process is highly conserved during evolution. This article discusses these recent findings and argues that cysts play an important and general role in germ line development.
AB - Germ cells in many vertebrate and invertebrate species initiate gametogenesis by forming groups of interconnected cells known as germline cysts. Recent studies using Xenopus, mouse and Drosophila are beginning to uncover the cellular and molecular mechanisms that control germline cyst formation and, in conjunction with morphological evidence, suggest that the process is highly conserved during evolution. This article discusses these recent findings and argues that cysts play an important and general role in germ line development.
UR - http://www.scopus.com/inward/record.url?scp=0033168559&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033168559&partnerID=8YFLogxK
U2 - 10.1016/S0962-8924(99)01594-9
DO - 10.1016/S0962-8924(99)01594-9
M3 - Review article
C2 - 10370240
AN - SCOPUS:0033168559
VL - 9
SP - 257
EP - 262
JO - Trends in Cell Biology
JF - Trends in Cell Biology
SN - 0962-8924
IS - 7
ER -