Germline cysts: A conserved phase of germ cell development?

Melissa E. Pepling; Margaret De Cuevas; Allan C. Sprading

doi:10.1016/S0962-8924(99)01594-9

Germline cysts: A conserved phase of germ cell development?

Melissa E. Pepling, Margaret De Cuevas, Allan C. Sprading

Research output: Contribution to journal › Review article › peer-review

177 Scopus citations

Abstract

Germ cells in many vertebrate and invertebrate species initiate gametogenesis by forming groups of interconnected cells known as germline cysts. Recent studies using Xenopus, mouse and Drosophila are beginning to uncover the cellular and molecular mechanisms that control germline cyst formation and, in conjunction with morphological evidence, suggest that the process is highly conserved during evolution. This article discusses these recent findings and argues that cysts play an important and general role in germ line development.

Original language	English (US)
Pages (from-to)	257-262
Number of pages	6
Journal	Trends in Cell Biology
Volume	9
Issue number	7
DOIs	https://doi.org/10.1016/S0962-8924(99)01594-9
State	Published - Jul 1 1999
Externally published	Yes

ASJC Scopus subject areas

Cell Biology

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title = "Germline cysts: A conserved phase of germ cell development?",

abstract = "Germ cells in many vertebrate and invertebrate species initiate gametogenesis by forming groups of interconnected cells known as germline cysts. Recent studies using Xenopus, mouse and Drosophila are beginning to uncover the cellular and molecular mechanisms that control germline cyst formation and, in conjunction with morphological evidence, suggest that the process is highly conserved during evolution. This article discusses these recent findings and argues that cysts play an important and general role in germ line development.",

author = "Pepling, {Melissa E.} and {De Cuevas}, Margaret and Sprading, {Allan C.}",

note = "Funding Information: We thank Leslie Coggins, Larry Etkins, Don Fawcett, David Gard, Robert Hardy, Tom Hays and Ting Xie for images. We thank Nicole Grieder and Erika Matunis for critically reading the manuscript. This work was supported by the Howard Hughes Medical Institute. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",

year = "1999",

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doi = "10.1016/S0962-8924(99)01594-9",

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pages = "257--262",

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TY - JOUR

T1 - Germline cysts

T2 - A conserved phase of germ cell development?

AU - Pepling, Melissa E.

AU - De Cuevas, Margaret

AU - Sprading, Allan C.

N1 - Funding Information: We thank Leslie Coggins, Larry Etkins, Don Fawcett, David Gard, Robert Hardy, Tom Hays and Ting Xie for images. We thank Nicole Grieder and Erika Matunis for critically reading the manuscript. This work was supported by the Howard Hughes Medical Institute. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.

PY - 1999/7/1

Y1 - 1999/7/1

N2 - Germ cells in many vertebrate and invertebrate species initiate gametogenesis by forming groups of interconnected cells known as germline cysts. Recent studies using Xenopus, mouse and Drosophila are beginning to uncover the cellular and molecular mechanisms that control germline cyst formation and, in conjunction with morphological evidence, suggest that the process is highly conserved during evolution. This article discusses these recent findings and argues that cysts play an important and general role in germ line development.

AB - Germ cells in many vertebrate and invertebrate species initiate gametogenesis by forming groups of interconnected cells known as germline cysts. Recent studies using Xenopus, mouse and Drosophila are beginning to uncover the cellular and molecular mechanisms that control germline cyst formation and, in conjunction with morphological evidence, suggest that the process is highly conserved during evolution. This article discusses these recent findings and argues that cysts play an important and general role in germ line development.

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DO - 10.1016/S0962-8924(99)01594-9

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JO - Trends in Cell Biology

JF - Trends in Cell Biology

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Germline cysts: A conserved phase of germ cell development?

Abstract

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