Feasibility of Electronic Medication Monitoring Among Adolescents and Emerging Adults with Sickle Cell Disease

Aimee K. Hildenbrand, Katherine M. Kidwell, Meghan E. McGrady, Charles T. Quinn, Lori E. Crosby, Constance A. Mara

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To examine the feasibility of using MEMS® bottles to assess adherence among adolescents and emerging adults with sickle cell disease. Patients and Methods: Eighteen non-Hispanic Black participants with HbSS (M = 17.8 years; 61% male) were given a MEMS® bottle to store hydroxyurea (n = 14) or deferasirox (n = 4). Results: One hundred percent initiated MEMS® use and 61% sustained use through the 18-week study; at follow-up, only 11% returned their bottle on time. Barriers to MEMS® use included medication changes and transition to adult care; facilitators included tip sheets and reminders. Conclusion: While MEMS® is acceptable to this population, ensuring sustained use and timely provision of bottles will require additional supports.

Original languageEnglish (US)
Pages (from-to)3167-3171
Number of pages5
JournalPatient Preference and Adherence
Volume17
DOIs
StatePublished - 2023

Keywords

  • adherence
  • medicine
  • MEMS
  • sickle cell anemia

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Social Sciences (miscellaneous)
  • Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
  • Health Policy

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