Feasibility of Electronic Medication Monitoring Among Adolescents and Emerging Adults with Sickle Cell Disease

Aimee K. Hildenbrand; Katherine M. Kidwell; Meghan E. McGrady; Charles T. Quinn; Lori E. Crosby; Constance A. Mara

doi:10.2147/PPA.S431595

Feasibility of Electronic Medication Monitoring Among Adolescents and Emerging Adults with Sickle Cell Disease

Aimee K. Hildenbrand, Katherine M. Kidwell, Meghan E. McGrady, Charles T. Quinn, Lori E. Crosby, Constance A. Mara

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: To examine the feasibility of using MEMS® bottles to assess adherence among adolescents and emerging adults with sickle cell disease. Patients and Methods: Eighteen non-Hispanic Black participants with HbSS (M = 17.8 years; 61% male) were given a MEMS® bottle to store hydroxyurea (n = 14) or deferasirox (n = 4). Results: One hundred percent initiated MEMS® use and 61% sustained use through the 18-week study; at follow-up, only 11% returned their bottle on time. Barriers to MEMS® use included medication changes and transition to adult care; facilitators included tip sheets and reminders. Conclusion: While MEMS® is acceptable to this population, ensuring sustained use and timely provision of bottles will require additional supports.

Original language	English (US)
Pages (from-to)	3167-3171
Number of pages	5
Journal	Patient Preference and Adherence
Volume	17
DOIs	https://doi.org/10.2147/PPA.S431595
State	Published - 2023

Keywords

MEMS
adherence
medicine
sickle cell anemia

ASJC Scopus subject areas

Medicine (miscellaneous)
Social Sciences (miscellaneous)
Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
Health Policy

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10.2147/PPA.S431595

Cite this

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title = "Feasibility of Electronic Medication Monitoring Among Adolescents and Emerging Adults with Sickle Cell Disease",

abstract = "Purpose: To examine the feasibility of using MEMS{\textregistered} bottles to assess adherence among adolescents and emerging adults with sickle cell disease. Patients and Methods: Eighteen non-Hispanic Black participants with HbSS (M = 17.8 years; 61% male) were given a MEMS{\textregistered} bottle to store hydroxyurea (n = 14) or deferasirox (n = 4). Results: One hundred percent initiated MEMS{\textregistered} use and 61% sustained use through the 18-week study; at follow-up, only 11% returned their bottle on time. Barriers to MEMS{\textregistered} use included medication changes and transition to adult care; facilitators included tip sheets and reminders. Conclusion: While MEMS{\textregistered} is acceptable to this population, ensuring sustained use and timely provision of bottles will require additional supports.",

keywords = "MEMS, adherence, medicine, sickle cell anemia",

author = "Hildenbrand, {Aimee K.} and Kidwell, {Katherine M.} and McGrady, {Meghan E.} and Quinn, {Charles T.} and Crosby, {Lori E.} and Mara, {Constance A.}",

note = "Publisher Copyright: {\textcopyright} 2023 Hildenbrand et al.",

year = "2023",

doi = "10.2147/PPA.S431595",

language = "English (US)",

volume = "17",

pages = "3167--3171",

journal = "Patient Preference and Adherence",

issn = "1177-889X",

publisher = "Dove Medical Press Ltd.",

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TY - JOUR

T1 - Feasibility of Electronic Medication Monitoring Among Adolescents and Emerging Adults with Sickle Cell Disease

AU - Hildenbrand, Aimee K.

AU - Kidwell, Katherine M.

AU - McGrady, Meghan E.

AU - Quinn, Charles T.

AU - Crosby, Lori E.

AU - Mara, Constance A.

PY - 2023

Y1 - 2023

N2 - Purpose: To examine the feasibility of using MEMS® bottles to assess adherence among adolescents and emerging adults with sickle cell disease. Patients and Methods: Eighteen non-Hispanic Black participants with HbSS (M = 17.8 years; 61% male) were given a MEMS® bottle to store hydroxyurea (n = 14) or deferasirox (n = 4). Results: One hundred percent initiated MEMS® use and 61% sustained use through the 18-week study; at follow-up, only 11% returned their bottle on time. Barriers to MEMS® use included medication changes and transition to adult care; facilitators included tip sheets and reminders. Conclusion: While MEMS® is acceptable to this population, ensuring sustained use and timely provision of bottles will require additional supports.

AB - Purpose: To examine the feasibility of using MEMS® bottles to assess adherence among adolescents and emerging adults with sickle cell disease. Patients and Methods: Eighteen non-Hispanic Black participants with HbSS (M = 17.8 years; 61% male) were given a MEMS® bottle to store hydroxyurea (n = 14) or deferasirox (n = 4). Results: One hundred percent initiated MEMS® use and 61% sustained use through the 18-week study; at follow-up, only 11% returned their bottle on time. Barriers to MEMS® use included medication changes and transition to adult care; facilitators included tip sheets and reminders. Conclusion: While MEMS® is acceptable to this population, ensuring sustained use and timely provision of bottles will require additional supports.

KW - MEMS

KW - adherence

KW - medicine

KW - sickle cell anemia

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ER -

Feasibility of Electronic Medication Monitoring Among Adolescents and Emerging Adults with Sickle Cell Disease

Abstract

Keywords

ASJC Scopus subject areas

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