Extended retrograde amnesia gradients: Peripheral epinephrine and frontal cortex stimulation

Paul E. Gold, Judith A. Reigel

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


This experiment examined the possibility that hormonal responses to training may increase the susceptibility of memory to an amnestic agent. As long as one week after training, rats that received a subcutaneous epinephrine injection shortly before electrical stimulation of frontal cortex exhibited amnesia on later retention tests. These findings suggest that retrograde amnesia gradients may reflect, in part, maximum susceptibility to amnesia shortly after training because the effects on memory of an amnestic agent are potentiated by the neuroendocrine response to training.

Original languageEnglish (US)
Pages (from-to)1101-1106
Number of pages6
JournalPhysiology and Behavior
Issue number6
StatePublished - Jun 1980
Externally publishedYes


  • Epinephrine
  • Frontal cortex stimulation
  • Gradients
  • Retrograde amnesia

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience


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