Experimental studies of SPECT scintimammography with combined cone-beam and parallel-beam collimators

A. Krol; D. H. Feiglin; K. R. Gangal; I. L. Coman; R. B. Salgado; E. D. Lipson; D. A. Karczewski; F. D. Thomas

doi:10.1117/12.480686

Experimental studies of SPECT scintimammography with combined cone-beam and parallel-beam collimators

A. Krol, D. H. Feiglin, K. R. Gangal, I. L. Coman, R. B. Salgado, E. D. Lipson, D. A. Karczewski, F. D. Thomas

Department of Physics

Research output: Contribution to journal › Conference Article › peer-review

Abstract

Conventional SPECT Tc-99m sestamibi scintimammography (STSM) has limited clinical utility due to fairly low radiopharmaceutical uptake in the breast tissue as compared to the heart and the liver. We investigated the use of a cone-beam collimator (CBC) to STSM. Each detector on a multi-headed gamma camera can be equipped with parallel-beam (PBC) or cone-beam collimators (CBC). PBC can provide truncation-free SPECT projection sets, while CBC offers increased sensitivity in a limited field-of-view (FOV). Combined PBC and CBC SPECT data acquisition may provide improved lesion contrast and overall better imaging performance within CBC FOV with significantly reduced truncation artifacts in the reconstructed images. In this paper we evaluate the combined CBC&PBC SPECT method using a limited number of confirmed breast cancer patients and female chest phantoms with simulated breast lesions. We envision the combined CBC&PBC SPECT as a useful clinical tool in scintimammography.

Original language	English (US)
Pages (from-to)	563-569
Number of pages	7
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	5031
DOIs	https://doi.org/10.1117/12.480686
State	Published - 2003
Event	Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications - San Diego, CA, United States Duration: Feb 16 2003 → Feb 18 2003

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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title = "Experimental studies of SPECT scintimammography with combined cone-beam and parallel-beam collimators",

abstract = "Conventional SPECT Tc-99m sestamibi scintimammography (STSM) has limited clinical utility due to fairly low radiopharmaceutical uptake in the breast tissue as compared to the heart and the liver. We investigated the use of a cone-beam collimator (CBC) to STSM. Each detector on a multi-headed gamma camera can be equipped with parallel-beam (PBC) or cone-beam collimators (CBC). PBC can provide truncation-free SPECT projection sets, while CBC offers increased sensitivity in a limited field-of-view (FOV). Combined PBC and CBC SPECT data acquisition may provide improved lesion contrast and overall better imaging performance within CBC FOV with significantly reduced truncation artifacts in the reconstructed images. In this paper we evaluate the combined CBC&PBC SPECT method using a limited number of confirmed breast cancer patients and female chest phantoms with simulated breast lesions. We envision the combined CBC&PBC SPECT as a useful clinical tool in scintimammography.",

author = "A. Krol and Feiglin, {D. H.} and Gangal, {K. R.} and Coman, {I. L.} and Salgado, {R. B.} and Lipson, {E. D.} and Karczewski, {D. A.} and Thomas, {F. D.}",

year = "2003",

doi = "10.1117/12.480686",

language = "English (US)",

volume = "5031",

pages = "563--569",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications ; Conference date: 16-02-2003 Through 18-02-2003",

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TY - JOUR

T1 - Experimental studies of SPECT scintimammography with combined cone-beam and parallel-beam collimators

AU - Krol, A.

AU - Feiglin, D. H.

AU - Gangal, K. R.

AU - Coman, I. L.

AU - Salgado, R. B.

AU - Lipson, E. D.

AU - Karczewski, D. A.

AU - Thomas, F. D.

PY - 2003

Y1 - 2003

N2 - Conventional SPECT Tc-99m sestamibi scintimammography (STSM) has limited clinical utility due to fairly low radiopharmaceutical uptake in the breast tissue as compared to the heart and the liver. We investigated the use of a cone-beam collimator (CBC) to STSM. Each detector on a multi-headed gamma camera can be equipped with parallel-beam (PBC) or cone-beam collimators (CBC). PBC can provide truncation-free SPECT projection sets, while CBC offers increased sensitivity in a limited field-of-view (FOV). Combined PBC and CBC SPECT data acquisition may provide improved lesion contrast and overall better imaging performance within CBC FOV with significantly reduced truncation artifacts in the reconstructed images. In this paper we evaluate the combined CBC&PBC SPECT method using a limited number of confirmed breast cancer patients and female chest phantoms with simulated breast lesions. We envision the combined CBC&PBC SPECT as a useful clinical tool in scintimammography.

AB - Conventional SPECT Tc-99m sestamibi scintimammography (STSM) has limited clinical utility due to fairly low radiopharmaceutical uptake in the breast tissue as compared to the heart and the liver. We investigated the use of a cone-beam collimator (CBC) to STSM. Each detector on a multi-headed gamma camera can be equipped with parallel-beam (PBC) or cone-beam collimators (CBC). PBC can provide truncation-free SPECT projection sets, while CBC offers increased sensitivity in a limited field-of-view (FOV). Combined PBC and CBC SPECT data acquisition may provide improved lesion contrast and overall better imaging performance within CBC FOV with significantly reduced truncation artifacts in the reconstructed images. In this paper we evaluate the combined CBC&PBC SPECT method using a limited number of confirmed breast cancer patients and female chest phantoms with simulated breast lesions. We envision the combined CBC&PBC SPECT as a useful clinical tool in scintimammography.

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DO - 10.1117/12.480686

M3 - Conference Article

AN - SCOPUS:0042828861

SN - 0277-786X

VL - 5031

SP - 563

EP - 569

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Medical Imaging 2003: Physiology and Function: Methods, Systems, and Applications

Y2 - 16 February 2003 through 18 February 2003

ER -

Experimental studies of SPECT scintimammography with combined cone-beam and parallel-beam collimators

Abstract

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