TY - GEN
T1 - Expectation maximization SPECT reconstruction with a content-adaptive, singularity-based, mesh-domain, image model
AU - Lu, Yao
AU - Ye, Hongwei
AU - Xu, Yuesheng
AU - Hu, Xiaofei
AU - Vogelsang, Levon
AU - Shen, Lixin
AU - Feiglin, David
AU - Lipson, Edward David
AU - Krol, Andrzej
PY - 2008
Y1 - 2008
N2 - To improve the speed and quality of ordered-subsets expectation- maximization (OSEM) SPECT reconstruction, we have implemented a content-adaptive, singularity-based, mesh-domain, image model (CASMIM) with an accurate algorithm for estimation of the mesh-domain system matrix. A preliminary image, used to initialize CASMIM reconstruction, was obtained using pixel-domain OSEM. The mesh-domain representation of the image was produced by a 2D wavelet transform followed by Delaunay triangulation to obtain joint estimation of nodal locations and their activity values. A system matrix with attenuation compensation was investigated. Digital chest phantom SPECT was simulated and reconstructed. The quality of images reconstructed with OSEM-CASMIM is comparable to that from pixel-domain OSEM, but images are obtained five times faster by the CASMIM method.
AB - To improve the speed and quality of ordered-subsets expectation- maximization (OSEM) SPECT reconstruction, we have implemented a content-adaptive, singularity-based, mesh-domain, image model (CASMIM) with an accurate algorithm for estimation of the mesh-domain system matrix. A preliminary image, used to initialize CASMIM reconstruction, was obtained using pixel-domain OSEM. The mesh-domain representation of the image was produced by a 2D wavelet transform followed by Delaunay triangulation to obtain joint estimation of nodal locations and their activity values. A system matrix with attenuation compensation was investigated. Digital chest phantom SPECT was simulated and reconstructed. The quality of images reconstructed with OSEM-CASMIM is comparable to that from pixel-domain OSEM, but images are obtained five times faster by the CASMIM method.
KW - 2D wavelet transform
KW - EM algorithm
KW - Mesh-domain image reconstruction
KW - SPECT
UR - http://www.scopus.com/inward/record.url?scp=43149120915&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=43149120915&partnerID=8YFLogxK
U2 - 10.1117/12.773082
DO - 10.1117/12.773082
M3 - Conference contribution
AN - SCOPUS:43149120915
SN - 9780819470973
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Medical Imaging 2008 - Physics of Medical Imaging
T2 - Medical Imaging 2008 - Physics of Medical Imaging
Y2 - 18 February 2008 through 21 February 2008
ER -