@inproceedings{188b450467954800842a35263c6a5ec4,
title = "Expectation maximization SPECT reconstruction with a content-adaptive, singularity-based, mesh-domain, image model",
abstract = "To improve the speed and quality of ordered-subsets expectation- maximization (OSEM) SPECT reconstruction, we have implemented a content-adaptive, singularity-based, mesh-domain, image model (CASMIM) with an accurate algorithm for estimation of the mesh-domain system matrix. A preliminary image, used to initialize CASMIM reconstruction, was obtained using pixel-domain OSEM. The mesh-domain representation of the image was produced by a 2D wavelet transform followed by Delaunay triangulation to obtain joint estimation of nodal locations and their activity values. A system matrix with attenuation compensation was investigated. Digital chest phantom SPECT was simulated and reconstructed. The quality of images reconstructed with OSEM-CASMIM is comparable to that from pixel-domain OSEM, but images are obtained five times faster by the CASMIM method.",
keywords = "2D wavelet transform, EM algorithm, Mesh-domain image reconstruction, SPECT",
author = "Yao Lu and Hongwei Ye and Yuesheng Xu and Xiaofei Hu and Levon Vogelsang and Lixin Shen and David Feiglin and Edward Lipson and Andrzej Krol",
year = "2008",
doi = "10.1117/12.773082",
language = "English (US)",
isbn = "9780819470973",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Medical Imaging 2008 - Physics of Medical Imaging",
note = "Medical Imaging 2008 - Physics of Medical Imaging ; Conference date: 18-02-2008 Through 21-02-2008",
}