Expectation maximization SPECT reconstruction with a content-adaptive, singularity-based, mesh-domain, image model

Yao Lu, Hongwei Ye, Yuesheng Xu, Xiaofei Hu, Levon Vogelsang, Lixin Shen, David Feiglin, Edward Lipson, Andrzej Krol

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

To improve the speed and quality of ordered-subsets expectation- maximization (OSEM) SPECT reconstruction, we have implemented a content-adaptive, singularity-based, mesh-domain, image model (CASMIM) with an accurate algorithm for estimation of the mesh-domain system matrix. A preliminary image, used to initialize CASMIM reconstruction, was obtained using pixel-domain OSEM. The mesh-domain representation of the image was produced by a 2D wavelet transform followed by Delaunay triangulation to obtain joint estimation of nodal locations and their activity values. A system matrix with attenuation compensation was investigated. Digital chest phantom SPECT was simulated and reconstructed. The quality of images reconstructed with OSEM-CASMIM is comparable to that from pixel-domain OSEM, but images are obtained five times faster by the CASMIM method.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2008 - Physics of Medical Imaging
DOIs
StatePublished - May 14 2008
EventMedical Imaging 2008 - Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 18 2008Feb 21 2008

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6913
ISSN (Print)1605-7422

Other

OtherMedical Imaging 2008 - Physics of Medical Imaging
CountryUnited States
CitySan Diego, CA
Period2/18/082/21/08

Keywords

  • 2D wavelet transform
  • EM algorithm
  • Mesh-domain image reconstruction
  • SPECT

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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    Lu, Y., Ye, H., Xu, Y., Hu, X., Vogelsang, L., Shen, L., Feiglin, D., Lipson, E., & Krol, A. (2008). Expectation maximization SPECT reconstruction with a content-adaptive, singularity-based, mesh-domain, image model. In Medical Imaging 2008 - Physics of Medical Imaging [69132F] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6913). https://doi.org/10.1117/12.773082