TY - GEN
T1 - Enzymatically triggered shape memory polymers direct cell alignment
AU - Buffington, Shelby L.
AU - Ali, Mathew M.
AU - Mather, Patrick T.
AU - Henderson, James H.
N1 - Publisher Copyright:
© 2019 Omnipress - All rights reserved.
PY - 2019
Y1 - 2019
N2 - Statement of Purpose Shape memory polymers (SMPs) have emerged as powerful platforms to study how cells respond to precise changes in their mechanical microenvironment. SMPs are a class of smart materials that change their shape in response to a stimulus, such as heat or hydration. Previously we have developed an SMP that responds to enzymatic activity that could enable SMPs to respond to physiological conditions in vivo, such as the presence of pathological cells.[1] The goal of this study was to study cell morphological and behavioral changes in response to enzymatically triggered shape changes that occur under isothermal conditions.
AB - Statement of Purpose Shape memory polymers (SMPs) have emerged as powerful platforms to study how cells respond to precise changes in their mechanical microenvironment. SMPs are a class of smart materials that change their shape in response to a stimulus, such as heat or hydration. Previously we have developed an SMP that responds to enzymatic activity that could enable SMPs to respond to physiological conditions in vivo, such as the presence of pathological cells.[1] The goal of this study was to study cell morphological and behavioral changes in response to enzymatically triggered shape changes that occur under isothermal conditions.
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M3 - Conference contribution
AN - SCOPUS:85065446194
T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
SP - 680
BT - Society for Biomaterials Annual Meeting and Exposition 2019
PB - Society for Biomaterials
T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Y2 - 3 April 2019 through 6 April 2019
ER -