The use of externally bonded carbon fiber reinforced polymer (CFRP) composites has become a viable choice for flexural strengthening reinforced concrete beams. A conventional method for preventing delamination of the CFRP sheet has been done by wrapping the beam ends with a transverse CFRP sheet. However, this is not possible in some types of flexural structures, i.e. reinforced concrete slab bridges. The only possible solution is the use of mechanical anchors, e.g. metallic anchors. In this paper, flexural responses of six full-scale CFRP strengthened beams with different types of end anchors including the 45° and 90° end wrapping CFRP anchor strips, steel anchor plate on plain surface, and steel anchor plate with special mounting detail have been studied. The results have shown that the effectiveness of metallic anchors is as good as CFRP anchor, where both increased the stiffness and strength of CFRP strengthened beams.