Effect of recent footshock on brain seizures and behavioral convulsions induced by electrical stimulation of the brain

Paul E. Gold, James L. McGaugh

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

These experiments examined the effect of electrical stimulation of the cortex on cortical seizures and behavioral convulsions in rats. The severity of the behavioral convulsion was attenuated by administering a footshock prior to the cortical stimulation. However, the FS did not attenuate the cortical seizure activity. The duration of the secondary afterdischarge was significantly longer in FS-treated animals. No other seizure parameters were significantly influenced by the footshock. The findings suggest that changes in cortical seizure patterns are not the basis for the observed changes in the behavioral convulsion patterns.

Original languageEnglish (US)
Pages (from-to)421-426
Number of pages6
JournalBehavioral Biology
Volume7
Issue number3
DOIs
StatePublished - Jun 1972
Externally publishedYes

ASJC Scopus subject areas

  • Environmental Science(all)
  • Earth and Planetary Sciences(all)

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