These experiments examined the effect of electrical stimulation of the cortex on cortical seizures and behavioral convulsions in rats. The severity of the behavioral convulsion was attenuated by administering a footshock prior to the cortical stimulation. However, the FS did not attenuate the cortical seizure activity. The duration of the secondary afterdischarge was significantly longer in FS-treated animals. No other seizure parameters were significantly influenced by the footshock. The findings suggest that changes in cortical seizure patterns are not the basis for the observed changes in the behavioral convulsion patterns.
ASJC Scopus subject areas
- Environmental Science(all)
- Earth and Planetary Sciences(all)