Direction Selectivity in Drosophila Proprioceptors Requires the Mechanosensory Channel Tmc

Liping He, Sarun Gulyanon, Mirna Mihovilovic Skanata, Doycho Karagyozov, Ellie S. Heckscher, Michael Krieg, Gavriil Tsechpenakis, Marc Gershow, W. Daniel Tracey

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

He et al. use high-speed confocal imaging to visualize the dynamic morphology of proprioceptive sensory neurons through the transparent skin of crawling Drosophila larvae. They use machine vision to create 3D models that describe how the neurons change during locomotion. They investigate the activity of the cells and the role of Tmc channels.

Original languageEnglish (US)
Pages (from-to)945-956.e3
JournalCurrent Biology
Volume29
Issue number6
DOIs
StatePublished - Mar 18 2019
Externally publishedYes

Keywords

  • Drosophila melanogaster
  • Tmc
  • behavior
  • mechanotransduction
  • microscopy
  • proprioception
  • sensory

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences

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