Development of the computational antibiotic screening platform (CLASP) to aid in the discovery of new antibiotics

Physics & Astronomy

• antibiotics 100%
• screening 62%
• platforms 60%
• molecules 19%
• drugs 15%
• permeability 13%
• nutrients 6%
• output 6%
• linings 5%
• bacteria 5%
• clocks 5%
• envelopes 4%
• sampling 4%
• proteins 4%
• transport properties 4%
• porosity 3%
• thermodynamics 3%
• kinetics 3%
• profiles 2%
• performance 2%
• energy 1%

Chemical Compounds

• Antimicrobial Agent 50%
• Carbapenem 15%
• Molecule 12%
• Permeability 12%
• Doripenem 9%
• Ertapenem 9%
• Meropenem 8%
• Imipenem 8%
• Resistance 6%
• Pipeline 6%
• Nutrient 5%
• Drug 5%
• Energy Barrier 4%
• Transport Property 4%
• Sampling 4%
• Reaction Yield 4%
• Time 3%
• Force 3%
• Rate Constant 3%
• Thermodynamics 3%
• Environment 2%
• Protein 2%
• Surface 1%
• Application 1%

Medicine & Life Sciences

• Anti-Bacterial Agents 47%
• Porins 21%
• Permeability 14%
• Carbapenems 12%
• Doripenem 9%
• Ertapenem 8%
• Small Molecule Libraries 7%
• Meropenem 6%
• Thermodynamics 6%
• Preclinical Drug Evaluations 6%
• Imipenem 6%
• Drug Discovery 5%
• Gram-Negative Bacteria 5%
• Microbial Drug Resistance 5%
• Nutrients 4%
• Kinetics 4%
• Pharmaceutical Preparations 2%
• Proteins 2%