TY - GEN
T1 - Development of a fully 3D system model in iterative expectation- maximization reconstruction for cone-beam SPECT
AU - Ye, Hongwei
AU - Vogelsang, Levon
AU - Feiglin, David H.
AU - Lipson, Edward D.
AU - Krol, Andrzej
PY - 2008
Y1 - 2008
N2 - In order to improve reconstructed image quality for cone-beam collimator SPECT, we have developed and implemented a fully 3D reconstruction, using an ordered subsets expectation maximization (OSEM) algorithm, along with a volumetric system model-cone-volume system model (CVSM), a modified attenuation compensation, and a 3D depth-and angle-dependent resolution and sensitivity correction. SPECT data were acquired in a 128×128 matrix, in 120 views with a single circular orbit. Two sets of numerical Défrise phantoms were used to simulate CBC SPECT scans, and low noise and scatter-free projection dataseis were obtained using the SimSET Monte Carlo package. The reconstructed images, obtained using OSEM with a line-length system model (LLSM) and a 3D Gaussian post-filter, and OSEM with FVSM and a 3D Gaussian post-filter were quantitatively studied. Overall improvement in the image quality has been observed, including better transaxial resolution, higher contrast-to-noise ratio between hot and cold disks, and better accuracy and lower bias in OSEM-CVSM, compared with OSEM-LLSM.
AB - In order to improve reconstructed image quality for cone-beam collimator SPECT, we have developed and implemented a fully 3D reconstruction, using an ordered subsets expectation maximization (OSEM) algorithm, along with a volumetric system model-cone-volume system model (CVSM), a modified attenuation compensation, and a 3D depth-and angle-dependent resolution and sensitivity correction. SPECT data were acquired in a 128×128 matrix, in 120 views with a single circular orbit. Two sets of numerical Défrise phantoms were used to simulate CBC SPECT scans, and low noise and scatter-free projection dataseis were obtained using the SimSET Monte Carlo package. The reconstructed images, obtained using OSEM with a line-length system model (LLSM) and a 3D Gaussian post-filter, and OSEM with FVSM and a 3D Gaussian post-filter were quantitatively studied. Overall improvement in the image quality has been observed, including better transaxial resolution, higher contrast-to-noise ratio between hot and cold disks, and better accuracy and lower bias in OSEM-CVSM, compared with OSEM-LLSM.
KW - Cone-beam collimator SPECT
KW - Cone-beam fully 3D reconstruction
KW - Volumetric system models
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U2 - 10.1117/12.772659
DO - 10.1117/12.772659
M3 - Conference contribution
AN - SCOPUS:43149087834
SN - 9780819470973
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Medical Imaging 2008 - Physics of Medical Imaging
T2 - Medical Imaging 2008 - Physics of Medical Imaging
Y2 - 18 February 2008 through 21 February 2008
ER -