Determination of the molecular lesions associated with loss-of-function transformer alleles of Drosophila melanogaster

Xiaoqing Yuan, John M. Belote

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Three mutant alleles of the transformer locus, trav1, trav2 and traenu, were analyzed genetically, and all were found to be functionally null alleles. The DNA sequences of these mutants revealed that they represent nonsense mutations that potentially encode truncated Tra polypeptides of 12, 61, and 90 amino acids, respectively.

Original languageEnglish (US)
Pages (from-to)369-370
Number of pages2
JournalBBA - Gene Structure and Expression
Volume1260
Issue number3
DOIs
StatePublished - Feb 21 1995

Keywords

  • (D. melanogaster)
  • DNA sequence
  • Mutant allele
  • Nonsense mutation
  • transformer locus

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

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