Designing quantum rod morphology and surface chemistry for optimum bioluminescence resonance energy transfer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have investigated the role that quantum rod (QR) morphology, composition, and surface chemistry play in resonance energy transfer phenomena. By fine-tuning the synthetic conditions, it is possible to tailor the aspect ratio of CdSe/CdS core-shell QRs from 2-8. The aspect ratio, as well as initial core diameter, determines the spectral properties of the QR, and theemission was tuned between 600 - 700 nm. These QR were then studied in resonance energy transfer studies with molecular fluorophores, fluorescent proteins, and bioluminescent enzymes. In order to accomplish functionalization, the biomaterials were attached to the QR interface via the N-terminus histag. The results indicate that the QR are ideal candidates for resonance energy transfer, due in large part to the increased stoichiometry provided by the rod morphology, andbetter spectral matching. The results also indicate that core location within the QR is particularly important when interpreting the energy transfer.

Original languageEnglish (US)
Title of host publicationCLEO: QELS_Fundamental Science, CLEO:QELS FS 2013
StatePublished - 2013
EventCLEO: QELS_Fundamental Science, CLEO:QELS FS 2013 - San Jose, CA, United States
Duration: Jun 9 2013Jun 14 2013

Other

OtherCLEO: QELS_Fundamental Science, CLEO:QELS FS 2013
CountryUnited States
CitySan Jose, CA
Period6/9/136/14/13

Fingerprint

Bioluminescence
bioluminescence
Surface chemistry
Energy transfer
rods
energy transfer
chemistry
Aspect ratio
Luminescent Proteins
Fluorophores
Biocompatible Materials
aspect ratio
Biomaterials
Stoichiometry
Enzymes
Tuning
Proteins
Chemical analysis
enzymes
stoichiometry

ASJC Scopus subject areas

  • Computer Networks and Communications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

Cite this

Designing quantum rod morphology and surface chemistry for optimum bioluminescence resonance energy transfer. / Maye, Mathew M.

CLEO: QELS_Fundamental Science, CLEO:QELS FS 2013. 2013.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Maye, MM 2013, Designing quantum rod morphology and surface chemistry for optimum bioluminescence resonance energy transfer. in CLEO: QELS_Fundamental Science, CLEO:QELS FS 2013. CLEO: QELS_Fundamental Science, CLEO:QELS FS 2013, San Jose, CA, United States, 6/9/13.
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