@inproceedings{84086fcea92140f1a28fac2d2f623ee4,
title = "Designing mechanical and electrical properties of microtubules to modulate gliding trajectories",
abstract = "Toward a multiplex molecular sorter, we propose a method to design electrical charge and mechanical stiffness of microtubules (MTs) for controlling trajectories of kinesin-propelled MTs regarded as molecular transporters in a microfluidic device. Seven MTs having different properties-persistence length (Lp) and surface charge density-were polymerized, and investigated the relationship between their properties and trajectories under a given electric field. We determined the optimal MT combination and device structure, leading to sort two MT groups with ∼85% precision in a PDMS device. Additive effects of mechanical and electrical properties achieved a high-precision MT sorting.",
keywords = "Elecrical charge, Kinesin, Microtubule, Molecular sorter, PDMS, Persistence length",
author = "N. Isozaki and H. Shintaku and H. Kotera and Hawkins, {T. L.} and Ross, {J. L.} and R. Yokokawa",
year = "2016",
language = "English (US)",
series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
publisher = "Chemical and Biological Microsystems Society",
pages = "120--121",
booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
note = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 ; Conference date: 09-10-2016 Through 13-10-2016",
}