Designer Collagen and Use Thereof

Brooke H. Russell (Inventor), Elizabeth M. Cosgriff-Hernandez (Inventor), Jose J. Rivera (Inventor), Magnus Hook (Inventor), Mariah S. Hahn (Inventor), Marvin Xuejun Xu (Inventor), Mary Beth Browning Monroe (Inventor), Neungseon Seo (Inventor)

Research output: Patent

Abstract

The present disclosure provides synthetic collagen and methods of making and using synthetic collagen that include a synthetic collagen that facilitates wound closure comprising an isolated and purified triple helical backbone protein that facilitates wound closure comprising one or more alteration in a triple helical backbone protein sequence, that stabilize the isolated and purified triple helical backbone protein and does not disrupt an additional collagen ligand interaction; and one or more integrin binding motifs, wherein the isolated and purified triple helical backbone protein facilitates wound closure.
Original languageEnglish (US)
StatePublished - Nov 16 2017

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