Abstract
This study tested the hypothesis that depressive symptoms would mediate the association of HIV-related stigma to medication adherence. We recruited HIV-infected men who have sex with men (MSM; N = 66; 66 % White, 23 % African-American) from an outpatient infectious disease clinic, and asked them to complete self-report measures. Mediational analyses showed that depressive symptoms fully mediated the association between HIV-related stigma and adherence. That is, stigma-related experiences were positively associated with depressive symptoms and negatively associated with adherence, and, in the final model, depressive symptoms remained a significant correlate of adherence while stigma did not. A test of the indirect effect of stigma on adherence through depressive symptoms was also significant (unstandardized b = −0.19; bootstrap 95 % CI −0.45 to −0.01). These results highlight the importance of treating depressive symptoms in interventions aiming to improve medication adherence among HIV-infected MSM.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1454-1459 |
| Number of pages | 6 |
| Journal | AIDS and Behavior |
| Volume | 19 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 6 2015 |
Keywords
- Depressive symptoms
- HIV
- MSM
- Medication adherence
- Stigma
ASJC Scopus subject areas
- Social Psychology
- Public Health, Environmental and Occupational Health
- Infectious Diseases