Control of the inflammatory response with poly(trolox ester) antioxidant nanoparticles

Patricia Wardwell, Paritosh Wattamwar, Thomas Dziubla, Rebecca Bader

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Poly(trolox ester) nanoparticles were screened for anti-inflammatory properties on two different rheumatoid arthritis cell lines. Trolox was polymerized to two different molecular weights and formed into nanoparticles, which were added to cultures of interleukin-1β stimulated MH7A synovial fibroblast cells and macrophage-like U937 cells. Poly(trolox ester) nanoparticles effectively reduced the secretion of pro-inflammatory mediators by both cell types.

Original languageEnglish (US)
Title of host publication2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012
Pages297-298
Number of pages2
DOIs
StatePublished - Jun 29 2012
Event38th Annual Northeast Bioengineering Conference, NEBEC 2012 - Philadelphia, PA, United States
Duration: Mar 16 2012Mar 18 2012

Publication series

Name2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012

Other

Other38th Annual Northeast Bioengineering Conference, NEBEC 2012
CountryUnited States
CityPhiladelphia, PA
Period3/16/123/18/12

ASJC Scopus subject areas

  • Bioengineering

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