Complexes of the {ReVOX2}+ (X = Cl, Br) core with single amino acid chelate derivatives

Lihui Wei, John Babich, Jon Zubieta

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The reactions of 1 equiv. of the ligand 3-(ethoxycarbonylmethyl-pyridin-2- ylmethyl-amino)-propionic acid methyl ester (2) with the Re(V) starting materials [ReOX3(PPh3)2] (X = Cl, Br) in refluxing chloroform yielded the Re(V)-oxo dihalide complexes [ReOX 2{(C5H4NCH2)N(CH2CO 2)(C2H4CO2CH3)}] (X = Cl, 3; X = Br, 4). The complexes were characterized by elemental analysis, NMR and IR spectroscopy, cyclic voltammetry and X-ray crystallography. Complex 3 displays distorted octahedral coordination geometry with the tridentate ligand coordinating facially to the Re(V) center. The carboxylate oxygen atom occupies an axial site trans to the ReO bond. The two chlorine atoms consequently adopt a cis configuration.

Original languageEnglish (US)
Pages (from-to)2413-2421
Number of pages9
JournalInorganica Chimica Acta
Volume358
Issue number7
DOIs
StatePublished - Apr 15 2005

Keywords

  • Radiopharmaceutical design
  • Single amino acid chelates
  • {ReOX} core

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

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