Comparisons of the effects of guanethidine, 6-hydroxydopamine and diethyldithiocarbamate on retention of passive avoidance

Tibor Palfai; Thomas J. Walsh

doi:10.1016/0091-3057(80)90211-7

Comparisons of the effects of guanethidine, 6-hydroxydopamine and diethyldithiocarbamate on retention of passive avoidance

Tibor Palfai, Thomas J. Walsh

Department of Psychology

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Depending on the dose levels, guanethidine and diethyldithiocarbamate produced time dependent amnesia for a one-trial passive avoidance task. 6-Hydroxydopamine given at any dose level or at any time interval before or after training did not result in retention deficits. The results were discussed in terms of the effects of these agents on peripheral biogenic amines and the possible role of these amines in memory formation.

Original language	English (US)
Pages (from-to)	805-809
Number of pages	5
Journal	Pharmacology, Biochemistry and Behavior
Volume	13
Issue number	6
DOIs	https://doi.org/10.1016/0091-3057(80)90211-7
State	Published - Dec 1980

Keywords

Amnesia
Antiadrenergic
Biogenic amines
Drugs
Memory

ASJC Scopus subject areas

Biochemistry
Toxicology
Pharmacology
Clinical Biochemistry
Biological Psychiatry
Behavioral Neuroscience

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10.1016/0091-3057(80)90211-7

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AB - Depending on the dose levels, guanethidine and diethyldithiocarbamate produced time dependent amnesia for a one-trial passive avoidance task. 6-Hydroxydopamine given at any dose level or at any time interval before or after training did not result in retention deficits. The results were discussed in terms of the effects of these agents on peripheral biogenic amines and the possible role of these amines in memory formation.

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KW - Antiadrenergic

KW - Biogenic amines

KW - Drugs

KW - Memory

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Comparisons of the effects of guanethidine, 6-hydroxydopamine and diethyldithiocarbamate on retention of passive avoidance

Abstract

Keywords

ASJC Scopus subject areas

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