Catalytic peptide assemblies

O. Zozulia, M. A. Dolan, Ivan Korendovych

Research output: Contribution to journalReview article

20 Citations (Scopus)

Abstract

Self-assembly of molecules often results in new emerging properties. Even very short peptides can self-assemble into structures with a variety of physical and structural characteristics. Remarkably, many peptide assemblies show high catalytic activity in model reactions reaching efficiencies comparable to those found in natural enzymes by weight. In this review, we discuss different strategies used to rationally develop self-assembled peptide catalysts with natural and unnatural backbones as well as with metal-containing cofactors.

Original languageEnglish (US)
Pages (from-to)3621-3639
Number of pages19
JournalChemical Society Reviews
Volume47
Issue number10
DOIs
StatePublished - May 21 2018

Fingerprint

Peptides
Self assembly
Catalyst activity
Metals
Catalysts
Molecules
Enzymes

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Catalytic peptide assemblies. / Zozulia, O.; Dolan, M. A.; Korendovych, Ivan.

In: Chemical Society Reviews, Vol. 47, No. 10, 21.05.2018, p. 3621-3639.

Research output: Contribution to journalReview article

Zozulia, O. ; Dolan, M. A. ; Korendovych, Ivan. / Catalytic peptide assemblies. In: Chemical Society Reviews. 2018 ; Vol. 47, No. 10. pp. 3621-3639.
@article{76da511af0c34b98a0ef7a73813e5826,
title = "Catalytic peptide assemblies",
abstract = "Self-assembly of molecules often results in new emerging properties. Even very short peptides can self-assemble into structures with a variety of physical and structural characteristics. Remarkably, many peptide assemblies show high catalytic activity in model reactions reaching efficiencies comparable to those found in natural enzymes by weight. In this review, we discuss different strategies used to rationally develop self-assembled peptide catalysts with natural and unnatural backbones as well as with metal-containing cofactors.",
author = "O. Zozulia and Dolan, {M. A.} and Ivan Korendovych",
year = "2018",
month = "5",
day = "21",
doi = "10.1039/c8cs00080h",
language = "English (US)",
volume = "47",
pages = "3621--3639",
journal = "Chemical Society Reviews",
issn = "0306-0012",
publisher = "Royal Society of Chemistry",
number = "10",

}

TY - JOUR

T1 - Catalytic peptide assemblies

AU - Zozulia, O.

AU - Dolan, M. A.

AU - Korendovych, Ivan

PY - 2018/5/21

Y1 - 2018/5/21

N2 - Self-assembly of molecules often results in new emerging properties. Even very short peptides can self-assemble into structures with a variety of physical and structural characteristics. Remarkably, many peptide assemblies show high catalytic activity in model reactions reaching efficiencies comparable to those found in natural enzymes by weight. In this review, we discuss different strategies used to rationally develop self-assembled peptide catalysts with natural and unnatural backbones as well as with metal-containing cofactors.

AB - Self-assembly of molecules often results in new emerging properties. Even very short peptides can self-assemble into structures with a variety of physical and structural characteristics. Remarkably, many peptide assemblies show high catalytic activity in model reactions reaching efficiencies comparable to those found in natural enzymes by weight. In this review, we discuss different strategies used to rationally develop self-assembled peptide catalysts with natural and unnatural backbones as well as with metal-containing cofactors.

UR - http://www.scopus.com/inward/record.url?scp=85047560243&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85047560243&partnerID=8YFLogxK

U2 - 10.1039/c8cs00080h

DO - 10.1039/c8cs00080h

M3 - Review article

C2 - 29594277

AN - SCOPUS:85047560243

VL - 47

SP - 3621

EP - 3639

JO - Chemical Society Reviews

JF - Chemical Society Reviews

SN - 0306-0012

IS - 10

ER -