Cancer Mutations in SPOP Put a Stop to Its Inter-compartmental Hops

Julia F. Riley, Thuy P. Dao, Carlos A. Castañeda

Research output: Contribution to journalShort survey

Abstract

In this issue of Molecular Cell, Bouchard et al. (2018) identify liquid-liquid phase separation as a mechanism for substrate-triggered localization of SPOP and ubiquitination machinery to different nuclear bodies and describe how cancer mutations disrupt this process. In this issue of Molecular Cell, Bouchard et al. (2018) identify liquid-liquid phase separation as a mechanism for substrate-triggered localization of SPOP and ubiquitination machinery to different nuclear bodies and describe how cancer mutations disrupt this process.

Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
JournalMolecular Cell
Volume72
Issue number1
DOIs
StatePublished - Oct 4 2018

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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