TY - JOUR
T1 - Calcium balance in crustaceans
T2 - Nutritional aspects of physiological regulation
AU - Zanotto, F. P.
AU - Wheatly, M. G.
N1 - Funding Information:
This collaboration was funded by a FAPESP grant 98/09756-9 and an international collaboration grant CNPq-NSF to FPZ and NSF grants IBN 9870374 and 0076035 to MGW. We also would like to thank Ricardo B. Oliveira and Felipe Pinheiro for whole animal data collection related to Ca balance.
PY - 2002/11/1
Y1 - 2002/11/1
N2 - Calcium homeostasis in crustaceans is influenced by their natural molting cycle that periodically requires replacement of the calcified exoskeleton in order for growth to occur. Whole body Ca balance transitions from intermolt (zero net flux) to premolt (net efflux) and postmolt (net influx at the rate of 2 mmolkg-1h-1). As such, molting provides a convenient model to study up- and down-regulation of epithelial Ca transporting proteins (such as Ca pumps and exchangers), the genes that encode them, and the steroid hormone (ecdysone) that putatively regulates the genes. Species residing in either freshwater or in terrestrial environments are more limited in their Ca availability than are marine species. Further the advance towards terrestriality is accompanied by decreased reliance upon branchial Ca uptake and increased reliance upon digestive uptake. This review will correlate Ca handling strategies with environment in semi-terrestrial and terrestrial crabs through examining environmental sources of Ca uptake. Ca homeostasis will also be discussed at the whole animal level, cellular, subcellular and molecular levels of regulation.
AB - Calcium homeostasis in crustaceans is influenced by their natural molting cycle that periodically requires replacement of the calcified exoskeleton in order for growth to occur. Whole body Ca balance transitions from intermolt (zero net flux) to premolt (net efflux) and postmolt (net influx at the rate of 2 mmolkg-1h-1). As such, molting provides a convenient model to study up- and down-regulation of epithelial Ca transporting proteins (such as Ca pumps and exchangers), the genes that encode them, and the steroid hormone (ecdysone) that putatively regulates the genes. Species residing in either freshwater or in terrestrial environments are more limited in their Ca availability than are marine species. Further the advance towards terrestriality is accompanied by decreased reliance upon branchial Ca uptake and increased reliance upon digestive uptake. This review will correlate Ca handling strategies with environment in semi-terrestrial and terrestrial crabs through examining environmental sources of Ca uptake. Ca homeostasis will also be discussed at the whole animal level, cellular, subcellular and molecular levels of regulation.
KW - Calcium homeostasis
KW - Calcium regulation
KW - Calcium transporters
KW - Environmental calcium
KW - Purified diets
UR - http://www.scopus.com/inward/record.url?scp=0036850010&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036850010&partnerID=8YFLogxK
U2 - 10.1016/S1095-6433(02)00202-7
DO - 10.1016/S1095-6433(02)00202-7
M3 - Article
C2 - 12443922
AN - SCOPUS:0036850010
SN - 1095-6433
VL - 133
SP - 645
EP - 660
JO - Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology
JF - Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology
IS - 3
ER -