Butanol Production Using Engineered Stremptomyces Coelicolor

Anthony Vortherms (Inventor), Joshua Lensbouer (Inventor), Robert Doyle (Inventor)

Research output: Patent


A method of producing butanal by optimizing the growth of Streptomyces using cellulose as food source, overexpressing a key ‘gate’ enzyme in butyric acid/butyraldehyde production, and knocking out the isobutyryl-CoA synthase gene to shunt the pathway. Optionally, the produced butanal can be isolated and converted into butanol.
Original languageEnglish (US)
Patent number9,034,616
StatePublished - Oct 7 2010


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