Blood Lead (Pb) Levels: Further Evidence for an Environmental Mechanism Explaining the Association Between Socioeconomic Status and Psychophysiological Dysregulation in Children

Brooks B Gump, Jacki Reihman, Paul Stewart, Ed Lonky, Douglas A. Granger, Karen A. Matthews

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Objective: The authors recently reported that blood lead (Pb) was a significant mediator for the positive association between socioeconomic status (SES) and peripheral vascular responses to acute stress in children (B. B. Gump et al., 2007). The present study considers the possibility that Pb may also mediate an association between SES and cortisol responses to acute stress. Design: Early childhood Pb exposure was tested as a mediator for cross-sectional associations between SES and cortisol responses. Main Outcome Measures: The primary outcome was cortisol responses to acute stress in 9.5-year-old children (N = 108). Results: Lower family income was associated with significantly greater cortisol levels following an acute stress task. A mediational analysis confirmed that Pb was a significant mediator for this association. Conclusion: These results reaffirm the importance of considering the chemical environment as well as social and psychological environment when evaluating psychophysiological effects of low SES.

Original languageEnglish (US)
Pages (from-to)614-620
Number of pages7
JournalHealth Psychology
Volume28
Issue number5
DOIs
StatePublished - Sep 2009
Externally publishedYes

Fingerprint

Social Class
Hydrocortisone
Social Environment
Blood Vessels
Outcome Assessment (Health Care)
Psychology
Lead

Keywords

  • children
  • cortisol
  • environmental toxicants
  • lead
  • socioeconomic status

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Applied Psychology

Cite this

Blood Lead (Pb) Levels : Further Evidence for an Environmental Mechanism Explaining the Association Between Socioeconomic Status and Psychophysiological Dysregulation in Children. / Gump, Brooks B; Reihman, Jacki; Stewart, Paul; Lonky, Ed; Granger, Douglas A.; Matthews, Karen A.

In: Health Psychology, Vol. 28, No. 5, 09.2009, p. 614-620.

Research output: Contribution to journalArticle

@article{d354539c83c44f59ba6883e3a820cacd,
title = "Blood Lead (Pb) Levels: Further Evidence for an Environmental Mechanism Explaining the Association Between Socioeconomic Status and Psychophysiological Dysregulation in Children",
abstract = "Objective: The authors recently reported that blood lead (Pb) was a significant mediator for the positive association between socioeconomic status (SES) and peripheral vascular responses to acute stress in children (B. B. Gump et al., 2007). The present study considers the possibility that Pb may also mediate an association between SES and cortisol responses to acute stress. Design: Early childhood Pb exposure was tested as a mediator for cross-sectional associations between SES and cortisol responses. Main Outcome Measures: The primary outcome was cortisol responses to acute stress in 9.5-year-old children (N = 108). Results: Lower family income was associated with significantly greater cortisol levels following an acute stress task. A mediational analysis confirmed that Pb was a significant mediator for this association. Conclusion: These results reaffirm the importance of considering the chemical environment as well as social and psychological environment when evaluating psychophysiological effects of low SES.",
keywords = "children, cortisol, environmental toxicants, lead, socioeconomic status",
author = "Gump, {Brooks B} and Jacki Reihman and Paul Stewart and Ed Lonky and Granger, {Douglas A.} and Matthews, {Karen A.}",
year = "2009",
month = "9",
doi = "10.1037/a0015611",
language = "English (US)",
volume = "28",
pages = "614--620",
journal = "Health Psychology",
issn = "0278-6133",
publisher = "American Psychological Association Inc.",
number = "5",

}

TY - JOUR

T1 - Blood Lead (Pb) Levels

T2 - Further Evidence for an Environmental Mechanism Explaining the Association Between Socioeconomic Status and Psychophysiological Dysregulation in Children

AU - Gump, Brooks B

AU - Reihman, Jacki

AU - Stewart, Paul

AU - Lonky, Ed

AU - Granger, Douglas A.

AU - Matthews, Karen A.

PY - 2009/9

Y1 - 2009/9

N2 - Objective: The authors recently reported that blood lead (Pb) was a significant mediator for the positive association between socioeconomic status (SES) and peripheral vascular responses to acute stress in children (B. B. Gump et al., 2007). The present study considers the possibility that Pb may also mediate an association between SES and cortisol responses to acute stress. Design: Early childhood Pb exposure was tested as a mediator for cross-sectional associations between SES and cortisol responses. Main Outcome Measures: The primary outcome was cortisol responses to acute stress in 9.5-year-old children (N = 108). Results: Lower family income was associated with significantly greater cortisol levels following an acute stress task. A mediational analysis confirmed that Pb was a significant mediator for this association. Conclusion: These results reaffirm the importance of considering the chemical environment as well as social and psychological environment when evaluating psychophysiological effects of low SES.

AB - Objective: The authors recently reported that blood lead (Pb) was a significant mediator for the positive association between socioeconomic status (SES) and peripheral vascular responses to acute stress in children (B. B. Gump et al., 2007). The present study considers the possibility that Pb may also mediate an association between SES and cortisol responses to acute stress. Design: Early childhood Pb exposure was tested as a mediator for cross-sectional associations between SES and cortisol responses. Main Outcome Measures: The primary outcome was cortisol responses to acute stress in 9.5-year-old children (N = 108). Results: Lower family income was associated with significantly greater cortisol levels following an acute stress task. A mediational analysis confirmed that Pb was a significant mediator for this association. Conclusion: These results reaffirm the importance of considering the chemical environment as well as social and psychological environment when evaluating psychophysiological effects of low SES.

KW - children

KW - cortisol

KW - environmental toxicants

KW - lead

KW - socioeconomic status

UR - http://www.scopus.com/inward/record.url?scp=70350514763&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70350514763&partnerID=8YFLogxK

U2 - 10.1037/a0015611

DO - 10.1037/a0015611

M3 - Article

C2 - 19751088

AN - SCOPUS:70350514763

VL - 28

SP - 614

EP - 620

JO - Health Psychology

JF - Health Psychology

SN - 0278-6133

IS - 5

ER -