Bioengineered Protein Pores

Liviu Movileanu (Inventor), Mohammad M. Mohammad (Inventor)

Research output: Patent

Abstract

A mutant Escherichia coli β-barrel monomeric protein pore bioengineered to remove a lumen-occluding domain and modify some of its extracellular domains. The modified protein, FhuA Δ/CΔ4L, forms a highly conductive pore as compared to other known pores and is capable of sensing large polypeptides and discriminating between modified protein analytes.
Original languageEnglish (US)
Patent number8,916,684
StatePublished - Jan 5 2012

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