Attenuation compensation in mesh-domain OSEM SPECT reconstruction

Levon Vogelsang, Yao Lu, Bo Yu, Andrzej Krol, Yuesheng Xu, Xiaofei Xu, David Feiglin, Edward Lipson

Research output: Chapter in Book/Entry/PoemConference contribution


A new method for attenuation compensation (AC) in mesh-domain SPECT OSEM reconstruction using strip-area approximation (SAAC) is introduced and compared to single-ray AC (SRAC). SAAC uses the polygonal area of the intersection of a mesh element (ME) and a tube-of-response (TOR) for defining an effective length of photon transit and an effective attenuation coefficient. This approach to AC is compared to SRAC, which defines the effective length of photon transit as the intersection of a single ray and a ME and the effective attenuation coefficient as the mean along the ray path. Comparative quantitative and qualitative analysis demonstrated that SAAC outperformed SRAC in terms of reconstruction image accuracy and quality.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2009
Subtitle of host publicationPhysics of Medical Imaging
StatePublished - 2009
EventMedical Imaging 2009: Physics of Medical Imaging - Lake Buena Vista, FL, United States
Duration: Feb 9 2009Feb 12 2009

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherMedical Imaging 2009: Physics of Medical Imaging
Country/TerritoryUnited States
CityLake Buena Vista, FL


  • Attenuation compensation
  • Mesh-domain SPECT image reconstruction

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging
  • Biomaterials


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