Associations of steps per day and peak cadence with arterial stiffness in older adults

Ludmila L.P. Cabral, Yuri A. Freire, Rodrigo A.V. Browne, Geovani A.D. Macêdo, Marcyo Câmara, Daniel Schwade, Luiz Fernando Farias-Junior, Ronildo Paulo-Pereira, Raíssa M. Silva, Telma M.A.M. Lemos, Tiago V. Barreira, Eduardo C. Costa

Research output: Contribution to journalArticlepeer-review

Abstract

Background: There is evidence showing an inverse association between steps/day and arterial stiffness in adults. However, the relationship of steps/day and peak cadence with arterial stiffness is poorly understood in older adults. This study aimed to investigate the association between steps/day and peak cadence with arterial stiffness in older adults. Methods: This cross-sectional study included 222 community-dwelling older adults (66 ± 5 years; 81.5% females; 70.3% with hypertension). Arterial stiffness was measured by aortic pulse wave velocity (aPWV). Steps/day and peak cadence were assessed by accelerometry. The participants were categorized according to the number of steps/day: sedentary <5000; low active 5000–7499; active 7500–9999; highly active 10,000+. Peak cadence was defined as the average of steps/day of the highest 30 min (not necessarily consecutive) for all valid days. Generalized linear models were used for data analyses. Results: The active (β = −0.34 m/s, 95% CI –0.60, −0.08) and highly active (β = −0.51 m/s, 95% CI –0.83, −0.20) groups had lower aPWV compared to the sedentary group. No significant difference was found between the low active group and the sedentary group (β = −0.21 m/s, 95% CI –0.46, 0.05). Every increment of 1000 steps/day was associated with a decrease of 0.05 m/s in the aPWV (95% CI –0.08, −0.02). Every increment of 10 steps/min in peak 30-min cadence was associated with a decrease of 0.05 m/s in aPWV (95% CI –0.09, −0.01). Conclusions: Our findings show that easy-to-use proxies of the volume (steps/day) and intensity (peak cadence) of ambulatory behavior are inversely associated with arterial stiffness in older adults. The inverse association of steps/day and peak cadence with arterial stiffness is dose-response.

Original languageEnglish (US)
Article number111628
JournalExperimental Gerontology
Volume157
DOIs
StatePublished - Jan 2022

Keywords

  • Accelerometry
  • Elderly
  • Exercise
  • Physical activity
  • Vascular stiffness

ASJC Scopus subject areas

  • Biochemistry
  • Aging
  • Molecular Biology
  • Genetics
  • Endocrinology
  • Cell Biology

Fingerprint

Dive into the research topics of 'Associations of steps per day and peak cadence with arterial stiffness in older adults'. Together they form a unique fingerprint.

Cite this