Anterograde and retrograde enhancement of 24-h memory by glucose in elderly humans

Carol A. Manning; Michael W. Parsons; Paul E. Gold

doi:10.1016/0163-1047(92)90351-4

Anterograde and retrograde enhancement of 24-h memory by glucose in elderly humans

Carol A. Manning, Michael W. Parsons, Paul E. Gold

Research output: Contribution to journal › Article › peer-review

110 Scopus citations

Abstract

The present experiment examined anterograde and retrograde enhancement of memory storage by glucose in elderly humans. Glucose (50 g) or saccharin was administered shortly before or immediately after acquisition of a narrative prose passage. Recall was tested 24 h later. Glucose administration before or after presentation of the material to be learned significantly improved recall 24 h later compared to performance in the saccharin condition. These findings suggest that glucose retroactively enhances memory storage processing in elderly humans and that the enhancement of memory outlasts the transient elevations in blood glucose levels after glucose ingestion.

Original language	English (US)
Pages (from-to)	125-130
Number of pages	6
Journal	Behavioral and Neural Biology
Volume	58
Issue number	2
DOIs	https://doi.org/10.1016/0163-1047(92)90351-4
State	Published - Sep 1992
Externally published	Yes

ASJC Scopus subject areas

Physiology

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title = "Anterograde and retrograde enhancement of 24-h memory by glucose in elderly humans",

abstract = "The present experiment examined anterograde and retrograde enhancement of memory storage by glucose in elderly humans. Glucose (50 g) or saccharin was administered shortly before or immediately after acquisition of a narrative prose passage. Recall was tested 24 h later. Glucose administration before or after presentation of the material to be learned significantly improved recall 24 h later compared to performance in the saccharin condition. These findings suggest that glucose retroactively enhances memory storage processing in elderly humans and that the enhancement of memory outlasts the transient elevations in blood glucose levels after glucose ingestion.",

author = "Manning, {Carol A.} and Parsons, {Michael W.} and Gold, {Paul E.}",

note = "Funding Information: 1 This work was supported by research grants from ONR (N0001489-J-1216), NIA (AG 07648), NSF (BNS-9012239), NIH (HD07323) and the Alzheimer's Association.",

year = "1992",

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doi = "10.1016/0163-1047(92)90351-4",

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AU - Parsons, Michael W.

AU - Gold, Paul E.

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PY - 1992/9

Y1 - 1992/9

N2 - The present experiment examined anterograde and retrograde enhancement of memory storage by glucose in elderly humans. Glucose (50 g) or saccharin was administered shortly before or immediately after acquisition of a narrative prose passage. Recall was tested 24 h later. Glucose administration before or after presentation of the material to be learned significantly improved recall 24 h later compared to performance in the saccharin condition. These findings suggest that glucose retroactively enhances memory storage processing in elderly humans and that the enhancement of memory outlasts the transient elevations in blood glucose levels after glucose ingestion.

AB - The present experiment examined anterograde and retrograde enhancement of memory storage by glucose in elderly humans. Glucose (50 g) or saccharin was administered shortly before or immediately after acquisition of a narrative prose passage. Recall was tested 24 h later. Glucose administration before or after presentation of the material to be learned significantly improved recall 24 h later compared to performance in the saccharin condition. These findings suggest that glucose retroactively enhances memory storage processing in elderly humans and that the enhancement of memory outlasts the transient elevations in blood glucose levels after glucose ingestion.

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Anterograde and retrograde enhancement of 24-h memory by glucose in elderly humans

Abstract

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