Amnesia produced by unilateral, subseizure, electrical stimulation of the amygdala in rats

Paul E. Gold, Rose Mary Edwards, James L. McGaugh

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Rats were trained on a one-trial inhibitory (passive) avoidance task. Five seconds after the offset of the training footshock, animals received unilateral, subseizure electrical stimulation of the amygdala. When compared to either implanted or unimplanted control animals, those animals which received posttrial amygdala stimulation had a significant retention deficit. Histological examination of electrode placements indicated that maximal interference with retention was produced by stimulation of a small region of the amygdala in or near the basomedial nucleus. Increases in the stimulation train duration from 10 to 30 sec increased the degree of the retention deficit produced by the stimulation.

Original languageEnglish (US)
Pages (from-to)95-105
Number of pages11
JournalBehavioral Biology
Volume15
Issue number1
DOIs
StatePublished - Sep 1975
Externally publishedYes

ASJC Scopus subject areas

  • Environmental Science(all)
  • Earth and Planetary Sciences(all)

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