Amnesia produced by unilateral, subseizure, electrical stimulation of the amygdala in rats

Paul E. Gold; Rose Mary Edwards; James L. McGaugh

doi:10.1016/S0091-6773(75)92131-8

Amnesia produced by unilateral, subseizure, electrical stimulation of the amygdala in rats

Paul E. Gold, Rose Mary Edwards, James L. McGaugh

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Rats were trained on a one-trial inhibitory (passive) avoidance task. Five seconds after the offset of the training footshock, animals received unilateral, subseizure electrical stimulation of the amygdala. When compared to either implanted or unimplanted control animals, those animals which received posttrial amygdala stimulation had a significant retention deficit. Histological examination of electrode placements indicated that maximal interference with retention was produced by stimulation of a small region of the amygdala in or near the basomedial nucleus. Increases in the stimulation train duration from 10 to 30 sec increased the degree of the retention deficit produced by the stimulation.

Original language	English (US)
Pages (from-to)	95-105
Number of pages	11
Journal	Behavioral Biology
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/S0091-6773(75)92131-8
State	Published - Sep 1975
Externally published	Yes

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Environmental Science(all)
Earth and Planetary Sciences(all)

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Amnesia produced by unilateral, subseizure, electrical stimulation of the amygdala in rats

Abstract

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