Abstract
Rats were trained on a one-trial inhibitory (passive) avoidance task. Five seconds after the offset of the training footshock, animals received unilateral, subseizure electrical stimulation of the amygdala. When compared to either implanted or unimplanted control animals, those animals which received posttrial amygdala stimulation had a significant retention deficit. Histological examination of electrode placements indicated that maximal interference with retention was produced by stimulation of a small region of the amygdala in or near the basomedial nucleus. Increases in the stimulation train duration from 10 to 30 sec increased the degree of the retention deficit produced by the stimulation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 95-105 |
| Number of pages | 11 |
| Journal | Behavioral Biology |
| Volume | 15 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1975 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Physiology
- Medicine(all)
Cite this
Amnesia produced by unilateral, subseizure, electrical stimulation of the amygdala in rats. / Gold, Paul Ernest; Edwards, Rose Mary; McGaugh, James L.
In: Behavioral Biology, Vol. 15, No. 1, 1975, p. 95-105.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Amnesia produced by unilateral, subseizure, electrical stimulation of the amygdala in rats
AU - Gold, Paul Ernest
AU - Edwards, Rose Mary
AU - McGaugh, James L.
PY - 1975
Y1 - 1975
N2 - Rats were trained on a one-trial inhibitory (passive) avoidance task. Five seconds after the offset of the training footshock, animals received unilateral, subseizure electrical stimulation of the amygdala. When compared to either implanted or unimplanted control animals, those animals which received posttrial amygdala stimulation had a significant retention deficit. Histological examination of electrode placements indicated that maximal interference with retention was produced by stimulation of a small region of the amygdala in or near the basomedial nucleus. Increases in the stimulation train duration from 10 to 30 sec increased the degree of the retention deficit produced by the stimulation.
AB - Rats were trained on a one-trial inhibitory (passive) avoidance task. Five seconds after the offset of the training footshock, animals received unilateral, subseizure electrical stimulation of the amygdala. When compared to either implanted or unimplanted control animals, those animals which received posttrial amygdala stimulation had a significant retention deficit. Histological examination of electrode placements indicated that maximal interference with retention was produced by stimulation of a small region of the amygdala in or near the basomedial nucleus. Increases in the stimulation train duration from 10 to 30 sec increased the degree of the retention deficit produced by the stimulation.
UR - http://www.scopus.com/inward/record.url?scp=0016553852&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0016553852&partnerID=8YFLogxK
U2 - 10.1016/S0091-6773(75)92131-8
DO - 10.1016/S0091-6773(75)92131-8
M3 - Article
C2 - 1237290
AN - SCOPUS:0016553852
VL - 15
SP - 95
EP - 105
JO - Neurobiology of Learning and Memory
JF - Neurobiology of Learning and Memory
SN - 1074-7427
IS - 1
ER -