TY - JOUR
T1 - Age dependent changes in retention in rats
AU - Gold, Paul E.
AU - McGaugh, James L.
AU - Hankins, Linda L.
AU - Rose, Robert P.
AU - Vasquez, Beatriz J.
N1 - Funding Information:
'This research was supported by research grants AG 00469 and AG 01642 from the National Institute of Aging. *From the Department of Psychobiology, University of California. Irvinr, CA 927 17, U.S.A. 'Now at the Department of Psychology. Univerity of Virginia. Charlottewille. Virginia 22YOl. U.S.A. 'Now at the University of Texas Health Scicnce Center. Hotiston. 'Texas. U.S.A. 'Now at Albert Einstein College of Medicine. Bronx. New York 10461. U.S.A.
PY - 1982
Y1 - 1982
N2 - These experiments examined the retention of newly acquired responses in 70-day-, 1-year-, and 2-year-old (Fischer 344) rats. In the first experiment, the rats were trained in a one-trial inhibitory (passive) avoidance task and retention performance was tested after training-test intervals ranging from 2 hrs to 6 weeks. When tested 2 hrs after training, 2-year-old rats performed significantly better than did 70-day-old rats. However, at longer intervals, the decline in retention performance (i.e., rate of forgetting) varied directly with age. Two-year-old rats exhibited more rapid loss of the avoidance response than did 70-day-old rats. One-year-old rats exhibited intermediate rates of forgetting. A second experiment examined retention performance tested 1, 7, or 21 days after training in a discriminated avoidance task. In this task as well, the rate of decline in retention performance varied directly with age. Thus, these findings suggest that aged Fischer 344 rats forget recently acquired information more rapidly than do younger rats.
AB - These experiments examined the retention of newly acquired responses in 70-day-, 1-year-, and 2-year-old (Fischer 344) rats. In the first experiment, the rats were trained in a one-trial inhibitory (passive) avoidance task and retention performance was tested after training-test intervals ranging from 2 hrs to 6 weeks. When tested 2 hrs after training, 2-year-old rats performed significantly better than did 70-day-old rats. However, at longer intervals, the decline in retention performance (i.e., rate of forgetting) varied directly with age. Two-year-old rats exhibited more rapid loss of the avoidance response than did 70-day-old rats. One-year-old rats exhibited intermediate rates of forgetting. A second experiment examined retention performance tested 1, 7, or 21 days after training in a discriminated avoidance task. In this task as well, the rate of decline in retention performance varied directly with age. Thus, these findings suggest that aged Fischer 344 rats forget recently acquired information more rapidly than do younger rats.
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U2 - 10.1080/03610738208258395
DO - 10.1080/03610738208258395
M3 - Article
AN - SCOPUS:0019995210
SN - 0361-073X
VL - 8
SP - 53
EP - 58
JO - Experimental Aging Research
JF - Experimental Aging Research
IS - 1
ER -