Experimental testing of an active flow control system on a three-dimensional, nonconformal turret has been performed at a diameter based Reynolds number of 2.0 × 106. Active flow control was achieved using dynamic suction and various open and closed-loop feedback control algorithms in an effort to determine the most effective and efficient control scheme for reducing aero-optic distortions in the vicinity of the turret aperture. Dynamic surface pressure and PIV measurements have been used to better characterize and understand the flow field in order to evaluate the active control system. From this research, it has been shown that dynamic suction has the ability to manipulate the separated flow above the turret aperture and can significantly alter the characteristics of the aperture flow field. Open-loop control was shown to be the most efficient form of control when set to the proper suction levels, but the merit of closed-loop feedback control has also been shown, especially for cases where the aperture of the turret is dynamically pitching. Generally, open-loop control systems require scheduling of the active control system during pitching where a closed-loop control system would not due to the sensing capabilities.