Active Cell Culture via Shape Memory

James Henderson (Inventor), Kelly Burke (Inventor), Kevin Davis (Inventor), Patrick Mather (Inventor), Xiuling Xu (Inventor)

Research output: Patent

Abstract

Substrates for cell culture and tissue engineering bioreactors consisting of polymers that change their shape over time under stimulation by temperature change, hydration, degradation, or other means. A method of controlling cell culture using a biodegradable shape memory polymer, wherein shape changes can transfer stresses, strains, or both to adherent or otherwise connected cells such that the mechanical stimulus impacts cell development and the resulting properties of tissues.
Original languageEnglish (US)
Patent number8,404,484
StatePublished - Mar 10 2011

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Henderson, J., Burke, K., Davis, K., Mather, P., & Xu, X. (2011). Active Cell Culture via Shape Memory. (Patent No. 8,404,484).