Abstract
Rationale: Fatigue affects almost half of all people living with stroke. Stroke survivors rank understanding fatigue and how to reduce it as one of the highest research priorities. Methods: We convened an interdisciplinary, international group of clinical and pre-clinical researchers and lived experience experts. We identified four priority areas: (1) best measurement tools for research, (2) clinical identification of fatigue and potentially modifiable causes, (3) promising interventions and recommendations for future trials, and (4) possible biological mechanisms of fatigue. Cross-cutting themes were aphasia and the voice of people with lived experience. Working parties were formed and structured consensus building processes were followed. Results: We present 20 recommendations covering outcome measures for research, development, and testing of new interventions and priority areas for future research on the biology of post-stroke fatigue. We developed and recommend the use of the Stroke Fatigue Clinical Assessment Tool. Conclusions: By synthesizing current knowledge in post-stroke fatigue across clinical and pre-clinical fields, our work provides a roadmap for future research into post-stroke fatigue.
Original language | English (US) |
---|---|
Pages (from-to) | 133-144 |
Number of pages | 12 |
Journal | International Journal of Stroke |
Volume | 19 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2024 |
Keywords
- Stroke
- consensus
- fatigue
- measurement
- mechanisms
- recovery
- rehabilitation
ASJC Scopus subject areas
- Neurology
- Clinical Neurology