The synthesis of a new chiral ligand 1 based on the conformationally defined 1,7-dioxaspiro[5.5]undecane ring system is reported. Generation of the corresponding ligand 1-Ti(OiPr)4 complex as a catalyst and its use in the enantioselective ring opening reaction of cyclohexene oxide with TMSN3 is described.
|Original language||English (US)|
|Number of pages||8|
|State||Published - Dec 1 1997|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry