TY - JOUR
T1 - A Library of Fluorinated Electrophiles for Chemical Tagging and Materials Synthesis
AU - Kasper, Jonathan J.
AU - Hitro, Jamie E.
AU - Fitzgerald, Sabrina R.
AU - Schnitter, Joseph M.
AU - Rutowski, James J.
AU - Heck, John A.
AU - Steinbacher, Jeremy L.
N1 - Publisher Copyright:
© 2016 American Chemical Society.
PY - 2016/9/2
Y1 - 2016/9/2
N2 - Various applications could benefit from new fluorinated molecules that offer chemical handles for quickly functionalizing reactive surfaces and molecules. Herein, we report the synthesis of a library of fluorinated molecules that contain nonafluoro-tert-butyl groups and electrophilic handles, mostly acrylates and acrylamides. Featuring a variety of hydrophobic and hydrophilic linkers, these molecules could find use in polymer chemistry, biomaterials, biomedical imaging, and protein tagging.
AB - Various applications could benefit from new fluorinated molecules that offer chemical handles for quickly functionalizing reactive surfaces and molecules. Herein, we report the synthesis of a library of fluorinated molecules that contain nonafluoro-tert-butyl groups and electrophilic handles, mostly acrylates and acrylamides. Featuring a variety of hydrophobic and hydrophilic linkers, these molecules could find use in polymer chemistry, biomaterials, biomedical imaging, and protein tagging.
UR - http://www.scopus.com/inward/record.url?scp=84985995082&partnerID=8YFLogxK
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U2 - 10.1021/acs.joc.6b01572
DO - 10.1021/acs.joc.6b01572
M3 - Article
AN - SCOPUS:84985995082
SN - 0022-3263
VL - 81
SP - 8095
EP - 8103
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 17
ER -