A large-scale location-based social network to understanding the impact of human geo-social interaction patterns on vaccination strategies in an urbanized area

Wei Luo, Peng Gao, Susan Cassels

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Cities play an important role in fostering and amplifying the transmission of airborne diseases (e.g., influenza) because of dense human contacts. Before an outbreak of airborne diseases within a city, how to determine an appropriate containment area for effective vaccination strategies is unknown. This research treats airborne disease spreads as geo-social interaction patterns, because viruses transmit among different groups of people over geographical locations through human interactions and population movement. Previous research argued that an appropriate scale identified through human geo-social interaction patterns can provide great potential for effective vaccination. However, little work has been done to examine the effectiveness of such vaccination at large scales (e.g., city) that are characterized by spatially heterogeneous population distribution and movement. This article therefore aims to understand the impact of geo-social interaction patterns on effective vaccination in the urbanized area of Portland, Oregon. To achieve this goal, we simulate influenza transmission on a large-scale location-based social network to 1) identify human geo-social interaction patterns for designing effective vaccination strategies, and 2) and evaluate the efficacy of different vaccination strategies according to the identified geo-social patterns. The simulation results illustrate the effectiveness of vaccination strategies based on geo-social interaction patterns in containing the epidemic outbreak at the source. This research can provide evidence to inform public health approaches to determine effective scales in the design of disease control strategies.

Original languageEnglish (US)
Pages (from-to)78-87
Number of pages10
JournalComputers, Environment and Urban Systems
Volume72
DOIs
StatePublished - Nov 2018
Externally publishedYes

Keywords

  • Agent-based epidemic models
  • Geo-social interaction patterns
  • Geo-social scale
  • High performance computing
  • Infectious disease transmission and control
  • Location-based social network
  • Social network analysis

ASJC Scopus subject areas

  • Geography, Planning and Development
  • Ecological Modeling
  • Environmental Science(all)
  • Urban Studies

Fingerprint Dive into the research topics of 'A large-scale location-based social network to understanding the impact of human geo-social interaction patterns on vaccination strategies in an urbanized area'. Together they form a unique fingerprint.

  • Cite this