A fully monolithic microfluidic device for counting blood cells from raw blood

John Nguyen; Yuan Wei; Yi Zheng; Chen Wang; Yu Sun

doi:10.1109/MEMSYS.2015.7050983

A fully monolithic microfluidic device for counting blood cells from raw blood

John Nguyen, Yuan Wei, Yi Zheng, Chen Wang, Yu Sun

Research output: Chapter in Book/Entry/Poem › Conference contribution

Abstract

This paper reports a monolithic microfluidic device capable of complete blood constituent enumeration from raw blood. On-chip sample processing (e.g. dilution, lysis, and filtration) and downstream single cell measurement were fully integrated to enable sample preparation and single cell analysis from whole blood on a single device. The device consists of two parallel sub-systems that perform sample processing and electrical impedance measurements for measuring RBC and WBC parameters. Experimental characterization of patient blood samples validated the system's capability for performing on-chip raw blood processing and measurement.

Original language	English (US)
Title of host publication	2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	435-438
Number of pages	4
Edition	February
ISBN (Electronic)	9781479979554
DOIs	https://doi.org/10.1109/MEMSYS.2015.7050983
State	Published - Feb 26 2015
Externally published	Yes
Event	2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal Duration: Jan 18 2015 → Jan 22 2015

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Number	February
Volume	2015-February
ISSN (Print)	1084-6999

Conference

Conference	2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015
Country/Territory	Portugal
City	Estoril
Period	1/18/15 → 1/22/15

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

Access to Document

10.1109/MEMSYS.2015.7050983

Cite this

Nguyen, J., Wei, Y., Zheng, Y., Wang, C., & Sun, Y. (2015). A fully monolithic microfluidic device for counting blood cells from raw blood. In 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 (February ed., pp. 435-438). Article 7050983 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); Vol. 2015-February, No. February). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMSYS.2015.7050983

A fully monolithic microfluidic device for counting blood cells from raw blood. / Nguyen, John; Wei, Yuan; Zheng, Yi et al.
2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015. February. ed. Institute of Electrical and Electronics Engineers Inc., 2015. p. 435-438 7050983 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); Vol. 2015-February, No. February).

Research output: Chapter in Book/Entry/Poem › Conference contribution

Nguyen, J, Wei, Y, Zheng, Y, Wang, C & Sun, Y 2015, A fully monolithic microfluidic device for counting blood cells from raw blood. in 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015. February edn, 7050983, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), no. February, vol. 2015-February, Institute of Electrical and Electronics Engineers Inc., pp. 435-438, 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015, Estoril, Portugal, 1/18/15. https://doi.org/10.1109/MEMSYS.2015.7050983

Nguyen J, Wei Y, Zheng Y, Wang C, Sun Y. A fully monolithic microfluidic device for counting blood cells from raw blood. In 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015. February ed. Institute of Electrical and Electronics Engineers Inc. 2015. p. 435-438. 7050983. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); February). doi: 10.1109/MEMSYS.2015.7050983

Nguyen, John ; Wei, Yuan ; Zheng, Yi et al. / A fully monolithic microfluidic device for counting blood cells from raw blood. 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015. February. ed. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 435-438 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); February).

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A fully monolithic microfluidic device for counting blood cells from raw blood

Abstract

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