A fully monolithic microfluidic device for counting blood cells from raw blood

John Nguyen, Yuan Wei, Yi Zheng, Chen Wang, Yu Sun

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper reports a monolithic microfluidic device capable of complete blood constituent enumeration from raw blood. On-chip sample processing (e.g. dilution, lysis, and filtration) and downstream single cell measurement were fully integrated to enable sample preparation and single cell analysis from whole blood on a single device. The device consists of two parallel sub-systems that perform sample processing and electrical impedance measurements for measuring RBC and WBC parameters. Experimental characterization of patient blood samples validated the system's capability for performing on-chip raw blood processing and measurement.

Original languageEnglish (US)
Title of host publication2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages435-438
Number of pages4
EditionFebruary
ISBN (Electronic)9781479979554
DOIs
StatePublished - Feb 26 2015
Externally publishedYes
Event2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal
Duration: Jan 18 2015Jan 22 2015

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
NumberFebruary
Volume2015-February
ISSN (Print)1084-6999

Conference

Conference2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015
Country/TerritoryPortugal
CityEstoril
Period1/18/151/22/15

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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