A new detached-eddy simulation procedure, MBFLO, is described for the simulation of turbulent flow over/within arbitrary geometry. This new procedure represents the first step toward developing a turbulent technique that reduces the reliance on traditional turbulence modeling by directly solving for the larger-scale turbulence effects in regions where the computational grid is sufficient to resolve those scales. A goal of this effort has been to develop a detached-eddy simulation procedure whose time-averaged solution can replace current "steady" simulation results for design. Since detached-eddy simulation requires the solution of the unsteady Navier-Stokes equations on computational grids that are typically an order in magnitude more dense than their Reynolds-averaged counter-parts, special care has been taken to make this new procedure computationally efficient. This paper describes the data structure, parallelization, and automation techniques used to produce time-averaged, detached-eddy simulation predictions. Results for the turbulent flow through a turbine and compressor cascade at design and off-design conditions, respectively, are shown to illustrate the technique.