Quasispecies theory predicts that there is a critical mutation probability above which a viral population will go extinct. Above this threshold the virus loses the ability to replicate the best-adapted genotype, leading to a population composed of low replicating mutants that is eventually doomed. We propose a new branching model that shows that this is not necessarily so. That is, a population composed of ever changing mutants may survive.
- Branching process
- Random environment
ASJC Scopus subject areas
- Statistics and Probability
- Statistics, Probability and Uncertainty