2-Methylenetetrahydropyrans: Efficient partners in the carbonyl ene reaction

Guohua Liang, Dakin T. Sharum, Troy Lam, Nancy I. Totah

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


The carbonyl ene reaction of 2-methylenetetrahydropyrans provides a rapid, high yielding route for the preparation of β-hydroxydihydropyrans under mild conditions. This process provides a new entry for the synthesis of 2-substituted tetrahydropyrans and for the direct introduction of oxygen heterocycles into molecular frameworks.

Original languageEnglish (US)
Pages (from-to)5974-5977
Number of pages4
JournalOrganic Letters
Issue number23
StatePublished - Dec 6 2013

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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