2-Methylenetetrahydropyrans

Efficient partners in the carbonyl ene reaction

Guohua Liang, Dakin T. Sharum, Troy Lam, Nancy Totah

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The carbonyl ene reaction of 2-methylenetetrahydropyrans provides a rapid, high yielding route for the preparation of β-hydroxydihydropyrans under mild conditions. This process provides a new entry for the synthesis of 2-substituted tetrahydropyrans and for the direct introduction of oxygen heterocycles into molecular frameworks.

Original languageEnglish (US)
Pages (from-to)5974-5977
Number of pages4
JournalOrganic Letters
Volume15
Issue number23
DOIs
StatePublished - Dec 6 2013

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entry
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Oxygen
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ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

2-Methylenetetrahydropyrans : Efficient partners in the carbonyl ene reaction. / Liang, Guohua; Sharum, Dakin T.; Lam, Troy; Totah, Nancy.

In: Organic Letters, Vol. 15, No. 23, 06.12.2013, p. 5974-5977.

Research output: Contribution to journalArticle

Liang, Guohua ; Sharum, Dakin T. ; Lam, Troy ; Totah, Nancy. / 2-Methylenetetrahydropyrans : Efficient partners in the carbonyl ene reaction. In: Organic Letters. 2013 ; Vol. 15, No. 23. pp. 5974-5977.
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