Abstract
β-(1-Azulenyl)-l-alanine (AzAla) can be incorporated into the influenza A virus M2 proton channel. AzAla's sensitivity to the protonation state of the nearby histidines and the lack of environmental fluorescence dependence allow for direct and straightforward determination of histidine pKa values in ion channels.
Original language | English (US) |
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Pages (from-to) | 5347-5350 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 51 |
Issue number | 25 |
DOIs | |
State | Published - Mar 28 2015 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry