Sarah E Hall

Personal profile

Research interests

My research program uses Caenorhabditis elegans nematodes as a model system to investigate the molecular mechanisms of how early life stress affects adult behavior and physiology.

Education

Genetics, Ph.D., University of Chicago

1999 → 2004

Biochemistry & Genetics, B.S., Texas A and M University

1995 → 1998

Research Interests

C. elegans
RNAi
dauer
cellular memory
endocrine signaling
neuroscience
environmental programming

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Caenorhabditis elegans Medicine & Life Sciences

Centromere Medicine & Life Sciences

RNA Interference Medicine & Life Sciences

Pinus taeda Medicine & Life Sciences

Small Interfering RNA Medicine & Life Sciences

Arabidopsis Medicine & Life Sciences

Pheromones Medicine & Life Sciences

Genome Medicine & Life Sciences

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Projects 2013 2024

1 Active
2 Finished

Characterization of Endocrine Signaling and RNAi Pathways as Mechanisms Regulating Environmental Programming in C. elegans

Hall, S. E.

National Institute of General Medical Sciences/NIH/DHHS

6/17/19 → 5/31/24

Project: Research project

Environmental Programming of Neuronal Gene Expression by Endogenous RNAi Pathways

Hall, S. E.

National Institute of General Medical Sciences/NIH/DHHS

8/15/16 → 7/31/19

Project: Research project

Environmental Programming of Chromatin States Via RNAi Pathways

Hall, S. E.

American Cancer Society, Inc., State University of New York Upstate Medical University

7/1/13 → 12/31/14

Project: Research project

Research Output 2000 2018

420 Citations
9 h-Index
15 Article
1 Chapter

3 Citations (Scopus)

Early experiences mediate distinct adult gene expression and reproductive programs in Caenorhabditis elegans

Ow, M. C., Borziak, K., Nichitean, A. M., Dorus, S. & Hall, S. E., Feb 1 2018, In : PLoS Genetics. 14, 2, e1007219.

Research output: Contribution to journal › Article

Caenorhabditis elegans

gene expression

Gene Expression

Starvation

germ cells

6 Citations (Scopus)

Early Pheromone Experience Modifies a Synaptic Activity to Influence Adult Pheromone Responses of C. elegans

Hong, M., Ryu, L., Ow, M. C., Kim, J., Je, A. R., Chinta, S., Huh, Y. H., Lee, K. J., Butcher, R. A., Choi, H., Sengupta, P., Hall, S. E. & Kim, K., Oct 23 2017, In : Current Biology. 27, 20, p. 3168-3177.e3

Research output: Contribution to journal › Article

Pheromones

pheromones

Neurons

Avoidance Learning

Data storage equipment

4 Citations (Scopus)

Endogenous RNAi Pathways Are Required in Neurons for Dauer Formation in Caenorhabditis elegans

Bharadwaj, P. S. & Hall, S. E., Apr 1 2017, In : Genetics. 205, 4, p. 1503-1516 14 p.

Research output: Contribution to journal › Article

Pheromones

Caenorhabditis elegans

RNA Interference

Neurons

Starvation

7 Citations (Scopus)

Linking the environment, DAF-7/TGFβ signaling and LAG-2/DSL ligand expression in the germline stem cell niche

Pekar, O., Ow, M. C., Hui, K. Y., Noyes, M. B., Hall, S. E. & Jane Albert Hubbard, E., Aug 15 2017, In : Development (Cambridge). 144, 16, p. 2896-2906 11 p.

Research output: Contribution to journal › Article

Stem Cell Niche

Germ Cells

Ligands

Stem Cells

Notch Receptors

9 Citations (Scopus)

Developmental programming modulates olfactory behavior in C. elegans via endogenous RNAi pathways

Sims, J. R., Ow, M. C., Nishiguchi, M. A., Kim, K., Sengupta, P. & Hall, S. E., Jun 28 2016, In : eLife. 5, JUNE2016, e11642.

Research output: Contribution to journal › Article

Chromatin Assembly and Disassembly

Activities of Daily Living

RNA Interference

Chromatin

Phenotype

Activities 2015 2015

1 Oral presentation