• 1626 Citations
  • 25 h-Index
20012020

Research output per year

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Research Output

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Article
2009

Anticancer conjugates and cocktails based on methotrexate and nucleoside synergism

Vortherms, A. R., Dang, H. N. & Doyle, R. P., May 21 2009, In : Clinical Medicine: Oncology. 2009, 3, p. 19-26 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Exploring the implications of vitamin B12 conjugation to insulin on insulin receptor binding

Petrus, A. K., Allis, D. G., Smith, R. P., Fairchild, T. J. & Doyle, R. P., Mar 16 2009, In : ChemMedChem. 4, 3, p. 421-426 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Pyrophosphate-bridged complexes with picomolar toxicity

Ikotun, O. F., Higbee, E. M., Ouellette, W. & Doyle, R. P., Sep 1 2009, In : Journal of Inorganic Biochemistry. 103, 9, p. 1254-1264 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Targeting the cubilin receptor through the vitamin B12 uptake pathway: Cytotoxicity and mechanistic insight through fluorescent Re(I) delivery

Viola-Villegas, N., Rabideau, A. E., Bartholoma, M., Zubieta, J. & Doyle, R. P., Aug 27 2009, In : Journal of Medicinal Chemistry. 52, 16, p. 5253-5261 9 p.

Research output: Contribution to journalArticle

60 Scopus citations
2008

Functional characterization and metal ion specificity of the metal-citrate complex transporter from Streptomyces coelicolor

Lensbouer, J. J., Patel, A., Sirianni, J. P. & Doyle, R. P., Aug 1 2008, In : Journal of bacteriology. 190, 16, p. 5616-5623 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

On the evolutionary significance and metal-binding characteristics of a monolobal transferrin from Ciona intestinalis

Tinoco, A. D., Peterson, C. W., Lucchese, B., Doyle, R. P. & Valentine, A. M., Mar 4 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 9, p. 3268-3273 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Orthogonal ligation: A three piece assembly of a PNA-peptide-PNA conjugate

Burlina, F., Dixson, D. D., Doyle, R. P., Chassaing, G., Boddy, C. N., Dawson, P. & Offer, J., 2008, In : Chemical Communications. 24, p. 2785-2787 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Spin canting in an unprecedented three-dimensional pyrophosphate- and 2,2′-bipyrimidine-bridged cobalt(II) framework

Marino, N., Mastropietro, T. F., Armentano, D., De Munno, G., Doyle, R. P., Lloret, F. & Julve, M., Sep 29 2008, In : Dalton Transactions. 38, p. 5152-5154 3 p.

Research output: Contribution to journalArticle

34 Scopus citations

Synthesis, characterization, and in vitro assay of folic acid conjugates of 3′-azido-3′-deoxythymidine (AZT): Toward targeted AZT based anticancer therapeutics

Vortherms, A. R., Doyle, R. P., Gao, D., Debrah, O. & Sinko, P. J., Feb 1 2008, In : Nucleosides, Nucleotides and Nucleic Acids. 27, 2, p. 173-185 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

Synthesis, structural, magnetic and thermal characterization of {[Cu(bipy)]2(μ-HP2O7)(μ-Cl)} ·H2O

Ikotun, O. F., Higbee, E. M., Ouellette, W., Lloret, F., Julve, M. & Doyle, R. P., Nov 1 2008, In : European Journal of Inorganic Chemistry. 33, p. 5281-5286 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Synthesis, structural, thermal and magnetic characterization of a pyrophosphato-bridged cobalt(II) complex

Ikotun, O. F., Ouellette, W., Lloret, F., Kruger, P. E., Julve, M. & Doyle, R. P., Jun 1 2008, In : European Journal of Inorganic Chemistry. 17, p. 2691-2697 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Targeting gallium to cancer cells through the folate receptor

Viola-Villegas, N., Vortherms, A. & Doyle, R. P., Jan 1 2008, In : Drug Target Insights. 2008, 3, p. 13-25 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Targeting the folate receptor (FR): Imaging and cytotoxicity of Re I conjugates in FR-overexpressing cancer cells

Viola-Villegas, N., Rabideau, A. E., Cesnavicious, J., Zubieta, J. & Doyle, R. P., Sep 15 2008, In : ChemMedChem. 3, 9, p. 1387-1394 8 p.

Research output: Contribution to journalArticle

59 Scopus citations
2007

Metamorphosis of a butterfly: Synthesis, structural, thermal, magnetic and DFT characterisation of a ferromagnetically coupled tetranuclear copper(ii) complex

Doyle, R. P., Bauer, T., Julve, M., Lloret, F., Cano, J., Nieuwenhuyzen, M. & Kruger, P. E., Jan 1 2007, In : Dalton Transactions. 44, p. 5140-5147 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
14 Scopus citations

Synthesis and structural and magnetic characterization of {[(phen) 2Ni]2(μ-P2O7)}·27H 2O and {[(phen)2Mn]2(μ-P2O 7)}·13H2O: Rare examples of coordination complexes with the pyrophosphate ligand

Ikotun, O. F., Armatus, N. G., Julve, M., Kruger, P. E., Lloret, F., Nieuwenhuyzen, M. & Doyle, R. P., Aug 6 2007, In : Inorganic Chemistry. 46, 16, p. 6668-6674 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Vitamin B12 as a carrier for the oral delivery of insulin

Petrus, A. K., Vortherms, A. R., Fairchild, T. J. & Doyle, R. P., Dec 10 2007, In : ChemMedChem. 2, 12, p. 1717-1721 5 p.

Research output: Contribution to journalArticle

53 Scopus citations
2006

A molecular 'back-flip': The structural consequences of the crystal-to-crystal phase transition between [(phen)2CuCO 3]·11H2O and [(phen)2CuCO 3]·7H2O

Doyle, R. P., Nieuwenhuyzen, M. & Kruger, P. E., Nov 29 2006, In : CrystEngComm. 8, 12, p. 904-908 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Hydrogen-bond tuning of ferromagnetic interactions: Synthesis, structure and magnetic properties of polynuclear copper(II) complexes incorporating p-block oxo-anions

Doyle, R. P., Julve, M., Lloret, F., Nieuwenhuyzen, M. & Kruger, P. E., Jun 5 2006, In : Dalton Transactions. 17, p. 2081-2088 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Synthesis, structure and thermal analysis of the gallium complex of 1,4,7,10-tetraazacyclo-dodecane-N,N′,N″,N‴-tetraacetic acid (DOTA)

Viola, N. A., Rarig, R. S., Ouellette, W. & Doyle, R. P., Dec 25 2006, In : Polyhedron. 25, 18, p. 3457-3462 6 p.

Research output: Contribution to journalArticle

43 Scopus citations
2005

Polynuclear complexes with bridging pyrophosphate ligands: Synthesis and characterisation of {[(bipy)Cu(H2O)

Doyle, R. P., Nieuwenhuyzen, M. & Kruger, P. E., Dec 7 2005, In : Dalton Transactions. 23, p. 3745-3750 6 p.

Research output: Contribution to journalArticle

36 Scopus citations
2003
45 Scopus citations
2002

A dihydrogen arsenate-mediated supramolecular network: Crystal structure and magnetic properties of {|(bipy)Cu(μ-H2AsO4)(H 2AsO4)|2}n

Doyle, R. P., Kruger, P. E., Julve, M., Lloret, F. & Nieuwenhuyzen, M., Dec 1 2002, In : CrystEngComm. 4, 3, p. 13-16 4 p.

Research output: Contribution to journalArticle

20 Scopus citations
2001

Phenazine-2,3-diamine

Doyle, R. P., Kruger, P. E., Mackie, P. R. & Nieuwenhuyzen, M., Jan 1 2001, In : Acta Crystallographica, Section C: Crystal Structure Communications. 57, 1, p. 104-105 2 p.

Research output: Contribution to journalArticle

14 Scopus citations

Structure and magnetic properties of a pyrophosphate-bridged Cu(II) complex

Kruger, P. E., Doyle, R. P., Julve, M., Lloret, F. & Nieuwenhuyzen, M., Apr 9 2001, In : Inorganic Chemistry. 40, 8, p. 1726-1727 2 p.

Research output: Contribution to journalArticle

53 Scopus citations