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Dive into the research topics where Robert Patrick Doyle is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Targeting the GDF15-GFRAL System to Treat Nausea and Emesis
Doyle, R. P. (PI)
8/9/21 → 5/31/25
Project: Sponsored Project
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Second Generation GLP-1 Agonists without Nausea/emesis Side Effects
Doyle, R. P. (PI)
3/1/21 → 6/30/23
Project: Sponsored Project
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B12-chloroquine and B12-mRNA Conjugates Development in Combination with Intrinsic Factor
Doyle, R. P. (PI)
3/1/21 → 2/28/22
Project: Sponsored Project
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Appetite-Suppressing Effects of Novel Glucoregulatory Chimeric Peptides Devoid Nausea
Doyle, R. P. (PI)
6/1/20 → 5/31/23
Project: Sponsored Project
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Proposal to Investigate Magnesium Chelates of Interest of Balchem Corporation
Doyle, R. P. (PI)
9/9/19 → 12/31/21
Project: Sponsored Project
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Corrination mitigates peptide aggregation as exemplified for Glucagon
Liles, A., Cham, N., Opp, M. L., Tinsley, I. C., Chepurny, O. G., Holz, G. G. & Doyle, R. P., Jan 2024, In: Peptides. 171, 171134.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Reductions of food intake and body weight in diet-induced obese rats following chronic treatment with a monomeric peptide multiagonist
Elfers, C. T., Chichura, K. S., Ashlaw, E. F., Chepurny, O. G., Holz, G. G., Doyle, R. P. & Roth, C. L., Jul 2024, In: Clinical Nutrition. 43, 7, p. 1782-1790 9 p.Research output: Contribution to journal › Article › peer-review
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The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-dependent manner
Blevins, J. E., Honeycutt, M. K., Slattery, J. D., Goldberg, M., Rambousek, J. R., Tsui, E., Dodson, A. D., Shelton, K. A., Salemeh, T. S., Elfers, C. T., Chichura, K. S., Ashlaw, E. F., Zraika, S., Doyle, R. P. & Roth, C. L., 2024, In: Frontiers in Endocrinology. 15, 1432928.Research output: Contribution to journal › Article › peer-review
Open Access -
A peptide triple agonist of GLP-1, neuropeptide Y1, and neuropeptide Y2 receptors promotes glycemic control and weight loss
Chichura, K. S., Elfers, C. T., Salameh, T. S., Kamat, V., Chepurny, O. G., McGivney, A., Milliken, B. T., Holz, G. G., Applebey, S. V., Hayes, M. R., Sweet, I. R., Roth, C. L. & Doyle, R. P., Dec 2023, In: Scientific reports. 13, 1, 9554.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Creation of a Peptide Antagonist of the GFRAL-RET Receptor Complex for the Treatment of GDF15-Induced Malaise
Borner, T., Tinsley, I. C., Milliken, B. T., Doebley, S. A., Najjar, N. R., Kerwood, D. J., De Jonghe, B. C., Hayes, M. R. & Doyle, R. P., Aug 24 2023, In: Journal of Medicinal Chemistry. 66, 16, p. 11237-11249 13 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations
Press and Media
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Aortic valve disease, new weight loss drugs, help for aging parents
3/2/25
1 item of Media coverage
Press/Media: Expert Comment
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Peptide Drug Advances Being Made on Syracuse University Campus Working to Redefine Obesity, Diabetes Care
1/8/25
1 item of Media coverage
Press/Media: Expert Comment
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Peptide Drug Advances Being Made on Syracuse University Campus Working to Redefine Obesity, Diabetes Care
1/7/25
1 item of Media coverage
Press/Media: Expert Comment
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Peptide Drug Advances Being Made on Syracuse University Campus Working to Redefine Obesity, Diabetes Care
1/7/25
1 item of Media coverage
Press/Media: Expert Comment