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Dive into the research topics where Robert Patrick Doyle is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Targeting the GDF15-GFRAL System to Treat Nausea and Emesis
Doyle, R. P. (PI)
8/9/21 → 5/31/25
Project: Sponsored Project
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Second Generation GLP-1 Agonists without Nausea/emesis Side Effects
Doyle, R. P. (PI)
3/1/21 → 6/30/23
Project: Sponsored Project
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B12-chloroquine and B12-mRNA Conjugates Development in Combination with Intrinsic Factor
Doyle, R. P. (PI)
3/1/21 → 2/28/22
Project: Sponsored Project
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Appetite-Suppressing Effects of Novel Glucoregulatory Chimeric Peptides Devoid Nausea
Doyle, R. P. (PI)
6/1/20 → 5/31/23
Project: Sponsored Project
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Proposal to Investigate Magnesium Chelates of Interest of Balchem Corporation
Doyle, R. P. (PI)
9/9/19 → 12/31/21
Project: Sponsored Project
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Corrination mitigates peptide aggregation as exemplified for Glucagon
Liles, A., Cham, N., Opp, M. L., Tinsley, I. C., Chepurny, O. G., Holz, G. G. & Doyle, R. P., Jan 2024, In: Peptides. 171, 171134.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Reductions of food intake and body weight in diet-induced obese rats following chronic treatment with a monomeric peptide multiagonist
Elfers, C. T., Chichura, K. S., Ashlaw, E. F., Chepurny, O. G., Holz, G. G., Doyle, R. P. & Roth, C. L., Jul 2024, In: Clinical Nutrition. 43, 7, p. 1782-1790 9 p.Research output: Contribution to journal › Article › peer-review
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A peptide triple agonist of GLP-1, neuropeptide Y1, and neuropeptide Y2 receptors promotes glycemic control and weight loss
Chichura, K. S., Elfers, C. T., Salameh, T. S., Kamat, V., Chepurny, O. G., McGivney, A., Milliken, B. T., Holz, G. G., Applebey, S. V., Hayes, M. R., Sweet, I. R., Roth, C. L. & Doyle, R. P., Dec 2023, In: Scientific reports. 13, 1, 9554.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Creation of a Peptide Antagonist of the GFRAL-RET Receptor Complex for the Treatment of GDF15-Induced Malaise
Borner, T., Tinsley, I. C., Milliken, B. T., Doebley, S. A., Najjar, N. R., Kerwood, D. J., De Jonghe, B. C., Hayes, M. R. & Doyle, R. P., Aug 24 2023, In: Journal of Medicinal Chemistry. 66, 16, p. 11237-11249 13 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects
Asker, M., Krieger, J. P., Liles, A., Tinsley, I. C., Borner, T., Maric, I., Doebley, S., Furst, C. D., Börchers, S., Longo, F., Bhat, Y. R., De Jonghe, B. C., Hayes, M. R., Doyle, R. P. & Skibicka, K. P., Mar 2023, In: Diabetes, Obesity and Metabolism. 25, 3, p. 856-877 22 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations
Press and Media
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US Patent Issued to SYRACUSE UNIVERSITY on Sept. 17 for "Peptide drug improvement using vitamin B 12 and Haptocorrin binding substrate conjugates" (New York Inventor)
9/18/24
1 item of Media coverage
Press/Media: Expert Comment
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Australia Patent: Application for 'Pharmaceutical formulations and methods for delivering a therapeutic, diagnostic, or imaging agent to CD206' Lapses
5/24/24
1 item of Media coverage
Press/Media: Expert Comment
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Medicinal Chemist Named Jack and Laura H. Milton Endowed Professor
1/13/24
1 item of Media coverage
Press/Media: Expert Comment
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Medicinal Chemist Named Jack and Laura H. Milton Endowed Professor
1/12/24
1 item of Media coverage
Press/Media: Expert Comment