Research Output 1995 2017

  • 2395 Citations
  • 28 h-Index from Scopus
  • 66 Article
  • 2 Chapter
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2017

Interrogating Detergent Desolvation of Nanopore-Forming Proteins by Fluorescence Polarization Spectroscopy

Wolfe, A. J., Hsueh, Y. C., Blanden, A. R., Mohammad, M. M., Pham, B., Thakur, A. K., Loh, S. N., Chen, M. & Movileanu, L. Aug 1 2017 In : Analytical Chemistry. 89, 15, p. 8013-8020 8 p.

Research output: Contribution to journalArticle

Fluorescence
Polarization
Dicamba
Bronchiolo-Alveolar Adenocarcinoma
Automobiles
2016
5 Citations

Global redesign of a native β-barrel scaffold

Wolfe, A. J., Mohammad, M. M., Thakur, A. K. & Movileanu, L. Jan 1 2016 In : Biochimica et Biophysica Acta - Biomembranes. 1858, 1, p. 19-29A

Research output: Contribution to journalArticle

Porins
Proteins
Peptides
Erysipelothrix
Electrophysiology
1 Citations

The Transmembrane Domain of a Bicomponent ABC Transporter Exhibits Channel-Forming Activity

Mohammad, M. M., Tomita, N., Ohta, M. & Movileanu, L. Sep 16 2016 In : ACS Chemical Biology. 11, 9, p. 2506-2518 13 p.

Research output: Contribution to journalArticle

ATP-Binding Cassette Transporters
Proteins
Carrier Proteins
Nucleotides
Adenosine Triphosphate
6 Citations

Yeast V-ATPase Proteolipid Ring Acts as a Large-conductance Transmembrane Protein Pore

Couoh-Cardel, S., Hsueh, Y. C., Wilkens, S. & Movileanu, L. Apr 21 2016 In : Scientific Reports. 6, 24774

Research output: Contribution to journalArticle

Proteolipids
Porins
Adenosine Triphosphatases
Yeasts
Membrane Fusion
2015

Erratum: Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore (Molecular Pharmacology (2015) 87 (825-831))

Blanden, R., Yu, X., Aaron, J. W., Gilleran, J. A., Augeri, D. J., O'Dell, R. S., Olson, E. C., Kimball, S. D., Emge, T. J., Movileanu, L., Carpizo, D. R. & Loh, S. N. Dec 1 2015 In : Molecular Pharmacology. 88, 6, p. 1084 1 p.

Research output: Contribution to journalArticle

4 Citations

Quasithermodynamic contributions to the fluctuations of a protein nanopore

Cheneke, B. R., Van Den Berg, B. & Movileanu, L. Mar 20 2015 In : ACS Chemical Biology. 10, 3, p. 784-794 11 p.

Research output: Contribution to journalArticle

Nanopores
Proteins
Motor Skills
Cape Verde
Hemoperfusion
13 Citations

Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore

Blanden, A. R., Yu, X., Wolfe, A. J., Gilleran, J. A., Augeri, D. J., O'Dell, R. S., Olson, E. C., Kimball, S. D., Emge, T. J., Movileanu, L., Carpizo, D. R. & Loh, S. N. May 1 2015 In : Molecular Pharmacology. 87, 5, p. 825-831 7 p.

Research output: Contribution to journalArticle

Metallochaperones
Ionophores
Zinc
Neoplasms
Metals
2014
10 Citations

Watching single proteins using engineered nanopores

Movileanu, L. Mar 2014 In : Protein and Peptide Letters. 21, 3, p. 235-246 12 p.

Research output: Contribution to journalArticle

Nanopores
Proteins
Motor Skills
Molecules
Protein Engineering
2013
17 Citations

Determination of the quaternary structure of a bacterial ATP-binding cassette (ABC) transporter in living cells

Singh, D. R., Mohammad, M. M., Patowary, S., Stoneman, M. R., Oliver, J. A., Movileanu, L. & Raicu, V. Feb 2013 In : Integrative Biology (United Kingdom). 5, 2, p. 312-323 12 p.

Research output: Contribution to journalArticle

Bacterial Structures
ATP-Binding Cassette Transporters
Lipopolysaccharides
Castration
Pseudomonas aeruginosa
3 Citations

Does the lipid environment impact the open-state conductance of an engineered β-barrel protein nanopore?

Tomita, N., Mohammad, M. M., Niedzwiecki, D. J., Ohta, M. & Movileanu, L. Mar 2013 In : Biochimica et Biophysica Acta - Biomembranes. 1828, 3, p. 1057-1065 9 p.

Research output: Contribution to journalArticle

Nanopores
Lipids
Proteins
Motor Skills
Bibliography of Medicine
8 Citations

Entropy-enthalpy compensation of biomolecular systems in aqueous phase: A dry perspective

Movileanu, L. & Schiff, E. A. Jan 2013 In : Monatshefte fur Chemie. 144, 1, p. 59-65 7 p.

Research output: Contribution to journalArticle

Hemophilia A
Hemoperfusion
Acetanilides
Dibenzoxepins
Buccal Administration
1 Citations

Erratum: Sampling a biomarker of the human immunodeficiency virus across a synthetic nanopore (ACS Nano (2013) 7 DOI: 10.1021/nn400125c)

Niedzwiecki, D. J., Iyer, R., Borer, P. N. & Movileanu, L. Apr 23 2013 In : ACS Nano. 7, 4, p. 3731 1 p.

Research output: Contribution to journalArticle

31 Citations

Sampling a biomarker of the human immunodeficiency virus across a synthetic nanopore

Niedzwiecki, D. J., Iyer, R., Borer, P. N. & Movileanu, L. Apr 23 2013 In : ACS Nano. 7, 4, p. 3341-3350 10 p.

Research output: Contribution to journalArticle

proteins
Proteins
Motor Skills
Nanopores
stems
23 Citations

Toward understanding the outer membrane uptake of small molecules by Pseudomonas aeruginosa

Eren, E., Parkin, J., Adelanwa, A., Cheneke, B., Movileanu, L., Khalid, S. & Van Den Berg, B. Apr 26 2013 In : Journal of Biological Chemistry. 288, 17, p. 12042-12053 12 p.

Research output: Contribution to journalArticle

Ion Channels
Pseudomonas aeruginosa
Membranes
Bronchiolo-Alveolar Adenocarcinoma
Molecules
2012
13 Citations

An outer membrane protein undergoes enthalpy- and entropy-driven transitions

Cheneke, B. R., Indic, M., Van Den Berg, B. & Movileanu, L. Jul 3 2012 In : Biochemistry. 51, 26, p. 5348-5358 11 p.

Research output: Contribution to journalArticle

Acetanilides
Hemoperfusion
Hemophilia A
Entropy
Membrane Proteins
14 Citations

Cation selectivity is a conserved feature in the OccD subfamily of Pseudomonas aeruginosa

Liu, J., Wolfe, A. J., Eren, E., Vijayaraghavan, J., Indic, M., Van Den Berg, B. & Movileanu, L. Nov 2012 In : Biochimica et Biophysica Acta - Biomembranes. 1818, 11, p. 2908-2916 9 p.

Research output: Contribution to journalArticle

Ion Channels
Pseudomonas aeruginosa
Cations
Bronchiolo-Alveolar Adenocarcinoma
Proteins
46 Citations

Engineering a rigid protein tunnel for biomolecular detection

Mohammad, M. M., Iyer, R., Howard, K. R., McPike, M. P., Borer, P. N. & Movileanu, L. Jun 6 2012 In : Journal of the American Chemical Society. 134, 22, p. 9521-9531 11 p.

Research output: Contribution to journalArticle

Proteins
Nanopores
Motor Skills
Membrane Proteins
Communication Disorders
8 Citations

Inspection of the Engineered FhuA Δc/Δ4L Protein Nanopore by Polymer Exclusion

Niedzwiecki, D. J., Mohammad, M. M. & Movileanu, L. Nov 21 2012 In : Biophysical Journal. 103, 10, p. 2115-2124 10 p.

Research output: Contribution to journalArticle

Nanopores
Polymers
Proteins
Protein Engineering
Dextrans
19 Citations

OccK channels from pseudomonas aeruginosa exhibit diverse single-channel electrical signatures but conserved anion selectivity

Liu, J., Eren, E., Vijayaraghavan, J., Cheneke, B. R., Indic, M., Van Den Berg, B. & Movileanu, L. Mar 20 2012 In : Biochemistry. 51, 11, p. 2319-2330 12 p.

Research output: Contribution to journalArticle

Pseudomonas aeruginosa
Anions
Proteins
Substrates
Membrane Proteins
46 Citations

Substrate specificity within a family of outer membrane carboxylate channels

Eren, E., Vijayaraghavan, J., Liu, J., Cheneke, B. R., Touw, D. S., Lepore, B. W., Indic, M., Movileanu, L. & van den Berg, B. Jan 2012 In : PLoS biology.. 10, 1, e1001242

Research output: Contribution to journalArticle

Substrate Specificity
Ion Channels
Anti-Bacterial Agents
Bacteria
Membranes
2011
18 Citations

Analysis of gating transitions among the three major open states of the OpdK channel

Cheneke, B. R., Van Den Berg, B. & Movileanu, L. Jun 7 2011 In : Biochemistry. 50, 22, p. 4987-4997 11 p.

Research output: Contribution to journalArticle

Membrane Proteins
Proteins
Kinetics
Porins
Lipid Bilayers

Monitoring protein adsorption with solid-state nanopores

Niedzwiecki, D. J. & Movileanu, L. 2011 In : Journal of Visualized Experiments. 58, e3560

Research output: Contribution to journalArticle

Nanopores
Adsorption
Proteins
Motor Skills
Protein Binding

Monitoring protein adsorption with solid-state nanopores.

Niedzwiecki, D. J. & Movileanu, L. 2011 In : Journal of Visualized Experiments. 58

Research output: Contribution to journalArticle

Nanopores
Adsorption
Proteins
Motor Skills
Protein Binding
28 Citations

Redesign of a plugged β-barrel membrane protein

Mohammad, M. M., Howard, K. R. & Movileanu, L. Mar 11 2011 In : Journal of Biological Chemistry. 286, 10, p. 8000-8013 14 p.

Research output: Contribution to journalArticle

Membrane Proteins
Proteins
Protein Engineering
Bacterial Outer Membrane Proteins
Nanopores
2010
25 Citations

Facilitated translocation of polypeptides through a single nanopore

Bikwemu, R., Wolfe, A. J., Xing, X. & Movileanu, L. Nov 17 2010 In : Journal of Physics Condensed Matter. 22, 45, 454117

Research output: Contribution to journalArticle

polypeptides
Polypeptides
Nanopores
Peptides
Motor Skills
25 Citations

Impact of distant charge reversals within a robust β-barrel protein pore

Mohammad, M. M. & Movileanu, L. Jul 8 2010 In : Journal of Physical Chemistry B. 114, 26, p. 8750-8759 10 p.

Research output: Contribution to journalArticle

Protein Engineering
Porins
Hemolysin Proteins
Lipid Bilayers
Aspartic Acid
69 Citations

Single-molecule observation of protein adsorption onto an inorganic surface

Niedzwiecki, D. J., Grazul, J. & Movileanu, L. Aug 11 2010 In : Journal of the American Chemical Society. 132, 31, p. 10816-10822 7 p.

Research output: Contribution to journalArticle

Nanopores
Adsorption
Proteins
Edema Disease of Swine
Motor Skills
2009
112 Citations

Interrogating single proteins through nanopores: challenges and opportunities

Movileanu, L. Jun 2009 In : Trends in Biotechnology. 27, 6, p. 333-341 9 p.

Research output: Contribution to journalArticle

Nanopores
Proteins
Motor Skills
Nanomedicine
Porins
2008
73 Citations

Controlling a single protein in a nanopore through electrostatic traps

Mohammad, M. M., Prakash, S., Matouschek, A. & Movileanu, L. Mar 26 2008 In : Journal of the American Chemical Society. 130, 12, p. 4081-4088 8 p.

Research output: Contribution to journalArticle

Nanopores
Static Electricity
Proteins
Porins
Hemolysin Proteins
33 Citations

Crystal Structure of the Outer Membrane Protein OpdK from Pseudomonas aeruginosa

Biswas, S., Mohammad, M. M., Movileanu, L. & van den Berg, B. Jul 9 2008 In : Structure. 16, 7, p. 1027-1035 9 p.

Research output: Contribution to journalArticle

Pseudomonas aeruginosa
Membrane Proteins
Porins
Substrate Specificity
Gram-Negative Bacteria
50 Citations

Excursion of a single polypeptide into a protein pore: Simple physics, but complicated biology

Mohammad, M. M. & Movileanu, L. Jul 2008 In : European Biophysics Journal. 37, 6, p. 913-925 13 p.

Research output: Contribution to journalArticle

Porins
Physics
Peptides
Proteins
Static Electricity
58 Citations

Squeezing a single polypeptide through a nanopore

Movileanu, L. 2008 In : Soft Matter. 4, 5, p. 925-931 7 p.

Research output: Contribution to journalArticle

proteins
Motor Skills
polypeptides
molecules
Molecules
47 Citations

Transport at the nanoscale: Temperature dependence of ion conductance

Chimerel, C., Movileanu, L., Pezeshki, S., Winterhalter, M. & Kleinekathöfer, U. Nov 2008 In : European Biophysics Journal. 38, 1, p. 121-125 5 p.

Research output: Contribution to journalArticle

Nanopores
Ions
Temperature
Ion Transport
Salts
2007
93 Citations

Catalyzing the translocation of polypeptides through attractive interactions

Wolfe, A. J., Mohammad, M. M., Cheley, S., Bayley, H. & Movileanu, L. Nov 14 2007 In : Journal of the American Chemical Society. 129, 45, p. 14034-14041 8 p.

Research output: Contribution to journalArticle

Polypeptides
Peptides
Binding Sites
Binding sites
Proteins
62 Citations

Single-molecule electrophoresis of β-hairpin peptides by electrical recordings and Langevin dynamics simulations

Goodrich, C. P., Kirmizialtin, S., Huyghues-Despointes, B. M., Zhu, A., Scholtz, J. M., Makarov, D. E. & Movileanu, L. Apr 5 2007 In : Journal of Physical Chemistry B. 111, 13, p. 3332-3335 4 p.

Research output: Contribution to journalArticle

peptides
Peptides
porosity
folding
proteins
59 Citations

Structural insight into OprD substrate specificity

Biswas, S., Mohammad, M. M., Patel, D. R., Movileanu, L. & Van Den Berg, B. Nov 2007 In : Nature Structural and Molecular Biology. 14, 11, p. 1108-1109 2 p.

Research output: Contribution to journalArticle

Substrate Specificity
Gram-Negative Bacteria
Ion Channels
Constriction
Pseudomonas aeruginosa
2006
86 Citations

Temperature-responsive protein pores

Jung, Y., Bayley, H. & Movileanu, L. Nov 29 2006 In : Journal of the American Chemical Society. 128, 47, p. 15332-15340 9 p.

Research output: Contribution to journalArticle

Porins
Elastin
Peptides
Temperature
Polypeptides
12 Citations

Transbilayer pores induced by thickness fluctuations

Movileanu, L., Popescu, D., Ion, S. & Popescu, A. I. Aug 2006 In : Bulletin of Mathematical Biology. 68, 6, p. 1231-1255 25 p.

Research output: Contribution to journalArticle

Phospholipids
phospholipid
phospholipids
Unstable
Radius
2005
33 Citations

Ethanol-induced alterations of the antioxidant defense system in rat kidney

Dinu, D., Nechifor, M. T. & Movileanu, L. 2005 In : Journal of Biochemical and Molecular Toxicology. 19, 6, p. 386-395 10 p.

Research output: Contribution to journalArticle

Ethanol
Antioxidants
Kidney
Staphylococcal Pneumonia
Glutathione Reductase
163 Citations

Interactions of peptides with a protein pore

Movileanu, L., Schmittschmitt, J. P., Scholtz, J. M. & Bayley, H. Aug 2005 In : Biophysical Journal. 89, 2, p. 1030-1045 16 p.

Research output: Contribution to journalArticle

Porins
Peptides
Hemolysin Proteins
Membrane Potentials
Nuclear Pore Complex Proteins
2003
3 Citations

Chapter 5 Elastic properties of bilayer lipid membranes and pore formation

Popescu, D., Ion, S., Popescu, A. & Movileanu, L. 2003 In : Membrane Science and Technology. 7, C, p. 173-204 32 p.

Research output: Contribution to journalArticle

Lipid bilayers
73 Citations

Partitioning of individual flexible polymers into a nanoscopic protein pore

Movileanu, L., Cheley, S. & Bayley, H. Aug 1 2003 In : Biophysical Journal. 85, 2, p. 897-910 14 p.

Research output: Contribution to journalArticle

Porins
Polymers
Hemolysin Proteins
Ethylene Glycol
Biotechnology
2002
5 Citations

Comparative study of some energetic and steric parameters of the wild type and mutants HIV-1 protease: A way to explain the viral resistance

Avram, S., Movileanu, L., Mihailescu, D. & Flonta, M. L. Apr 2002 In : Journal of Cellular and Molecular Medicine. 6, 2, p. 251-260 10 p.

Research output: Contribution to journalArticle

HIV Protease
HIV-1
Edema Disease of Swine
Electrostatics
Static Electricity
32 Citations

Determination of base and backbone contributions to the thermodynamics of premelting and melting transitions in B DNA

Movileanu, L., Benevides, J. M. & Thomas, G. J. Sep 1 2002 In : Nucleic Acids Research. 30, 17, p. 3767-3777 11 p.

Research output: Contribution to journalArticle

Poly dA-dT
Thermodynamics
Freezing
DNA
Base Pairing
85 Citations

Subunit composition of a bicomponent toxin: Staphylococcal leukocidin forms an octameric transmembrane pore

Miles, G., Movileanu, L. & Bayley, H. 2002 In : Protein Science. 11, 4, p. 894-902 9 p.

Research output: Contribution to journalArticle

Leukocidins
Hemolysin Proteins
African horse sickness virus
Protein Engineering
Electrophoresis
66 Citations
Poly dA-dT
Freezing
Temperature
DNA
Melting
2001
138 Citations

Kinetics of duplex formation for individual DNA strands within a single protein nanopore

Howorka, S., Movileanu, L., Braha, O. & Bayley, H. Nov 6 2001 In : Proceedings of the National Academy of Sciences of the United States of America. 98, 23, p. 12996-13001 6 p.

Research output: Contribution to journalArticle

Nanopores
DNA
Proteins
Oligonucleotides
Porins
54 Citations

Location of a constriction in the lumen of a transmembrane pore by targeted covalent attachment of polymer molecules

Movileanu, L., Cheley, S., Howorka, S., Braha, O. & Bayley, H. 2001 In : Journal of General Physiology. 117, 3, p. 239-251 13 p.

Research output: Contribution to journalArticle

Constriction
Polymers
Cysteine
Crystallography
Hemolysin Proteins
74 Citations
Porins
Polymers
Hemolysin Proteins
Ethylene Glycol
Cysteine
2000
23 Citations

A protein pore with a single polymer chain tethered within the lumen

Howorka, S., Movileanu, L., Lu, X., Magnon, M., Cheley, S., Braha, O. & Bayley, H. Mar 22 2000 In : Journal of the American Chemical Society. 122, 11

Research output: Contribution to journalArticle

Porins
Polymers
Polyethylene glycols
Molecules
Hemolysin Proteins