• 2986 Citations
  • 31 h-Index
19952020

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Article
2020

Cyclic Activity of an Osmotically Stressed Liposome in a Finite Hypotonic Environment

Imran, A., Popescu, D. & Movileanu, L., Apr 7 2020, In : Langmuir. 36, 13, p. 3659-3666 8 p.

Research output: Contribution to journalArticle

2019

High-Throughput Screening of Protein-Detergent Complexes Using Fluorescence Polarization Spectroscopy

Wolfe, A. J., Parella, K. J. & Movileanu, L., Sep 1 2019, In : Current protocols in protein science. 97, 1, e96.

Research output: Contribution to journalArticle

Interactions of a Polypeptide with a Protein Nanopore under Crowding Conditions

Larimi, M. G., Mayse, L. A. & Movileanu, L., Apr 23 2019, In : ACS nano. 13, 4, p. 4469-4477 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Real-time measurement of protein–protein interactions at single-molecule resolution using a biological nanopore

Thakur, A. K. & Movileanu, L., Jan 1 2019, In : Nature Biotechnology. 37, 1, p. 96-104 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Single-molecule protein detection in a biofluid using a quantitative nanopore sensor

Thakur, A. K. & Movileanu, L., Sep 27 2019, In : ACS Sensors. 4, 9, p. 2320-2326 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Detergent Desorption of Membrane Proteins Exhibits Two Kinetic Phases

Wolfe, A. J., Gugel, J. F., Chen, M. & Movileanu, L., Apr 19 2018, In : Journal of Physical Chemistry Letters. 9, 8, p. 1913-1919 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Kinetics of Membrane Protein-Detergent Interactions Depend on Protein Electrostatics

Wolfe, A. J., Gugel, J. F., Chen, M. & Movileanu, L., Oct 18 2018, In : Journal of Physical Chemistry B. 122, 41, p. 9471-9481 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Aberrantly Large Single-Channel Conductance of Polyhistidine Arm-Containing Protein Nanopores

Thakur, A. K., Larimi, M. G., Gooden, K. & Movileanu, L., Sep 12 2017, In : Biochemistry. 56, 36, p. 4895-4905 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Interrogating Detergent Desolvation of Nanopore-Forming Proteins by Fluorescence Polarization Spectroscopy

Wolfe, A. J., Hsueh, Y. C., Blanden, A. R., Mohammad, M. M., Pham, B., Thakur, A. K., Loh, S. N., Chen, M. & Movileanu, L., Aug 1 2017, In : Analytical Chemistry. 89, 15, p. 8013-8020 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Quantification of Membrane Protein-Detergent Complex Interactions

Wolfe, A. J., Si, W., Zhang, Z., Blanden, A. R., Hsueh, Y. C., Gugel, J. F., Pham, B., Chen, M., Loh, S. N., Rozovsky, S., Aksimentiev, A. & Movileanu, L., Nov 9 2017, In : Journal of Physical Chemistry B. 121, 44, p. 10228-10241 14 p.

Research output: Contribution to journalArticle

11 Scopus citations
2016

Global redesign of a native β-barrel scaffold

Wolfe, A. J., Mohammad, M. M., Thakur, A. K. & Movileanu, L., Jan 1 2016, In : Biochimica et Biophysica Acta - Biomembranes. 1858, 1, p. 19-29A

Research output: Contribution to journalArticle

12 Scopus citations

The Transmembrane Domain of a Bicomponent ABC Transporter Exhibits Channel-Forming Activity

Mohammad, M. M., Tomita, N., Ohta, M. & Movileanu, L., Sep 16 2016, In : ACS Chemical Biology. 11, 9, p. 2506-2518 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Yeast V-ATPase Proteolipid Ring Acts as a Large-conductance Transmembrane Protein Pore

Couoh-Cardel, S., Hsueh, Y. C., Wilkens, S. & Movileanu, L., Apr 21 2016, In : Scientific reports. 6, 24774.

Research output: Contribution to journalArticle

19 Scopus citations
2015

Quasithermodynamic contributions to the fluctuations of a protein nanopore

Cheneke, B. R., Van Den Berg, B. & Movileanu, L., Mar 20 2015, In : ACS Chemical Biology. 10, 3, p. 784-794 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Synthetic metallochaperone ZMC1 rescues mutant p53 conformation by transporting zinc into cells as an ionophore

Blanden, A. R., Yu, X., Wolfe, A. J., Gilleran, J. A., Augeri, D. J., O'Dell, R. S., Olson, E. C., Kimball, S. D., Emge, T. J., Movileanu, L., Carpizo, D. R. & Loh, S. N., May 1 2015, In : Molecular Pharmacology. 87, 5, p. 825-831 7 p.

Research output: Contribution to journalArticle

37 Scopus citations
2014

Watching single proteins using engineered nanopores

Movileanu, L., Mar 2014, In : Protein and Peptide Letters. 21, 3, p. 235-246 12 p.

Research output: Contribution to journalArticle

12 Scopus citations
2013

Determination of the quaternary structure of a bacterial ATP-binding cassette (ABC) transporter in living cells

Singh, D. R., Mohammad, M. M., Patowary, S., Stoneman, M. R., Oliver, J. A., Movileanu, L. & Raicu, V., Feb 1 2013, In : Integrative Biology (United Kingdom). 5, 2, p. 312-323 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Does the lipid environment impact the open-state conductance of an engineered β-barrel protein nanopore?

Tomita, N., Mohammad, M. M., Niedzwiecki, D. J., Ohta, M. & Movileanu, L., Mar 1 2013, In : Biochimica et Biophysica Acta - Biomembranes. 1828, 3, p. 1057-1065 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Entropy-enthalpy compensation of biomolecular systems in aqueous phase: A dry perspective

Movileanu, L. & Schiff, E. A., Jan 1 2013, In : Monatshefte fur Chemie. 144, 1, p. 59-65 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Sampling a biomarker of the human immunodeficiency virus across a synthetic nanopore

Niedzwiecki, D. J., Iyer, R., Borer, P. N. & Movileanu, L., Apr 23 2013, In : ACS nano. 7, 4, p. 3341-3350 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Toward understanding the outer membrane uptake of small molecules by Pseudomonas aeruginosa

Eren, E., Parkin, J., Adelanwa, A., Cheneke, B., Movileanu, L., Khalid, S. & Van Den Berg, B., Apr 26 2013, In : Journal of Biological Chemistry. 288, 17, p. 12042-12053 12 p.

Research output: Contribution to journalArticle

38 Scopus citations
2012

An outer membrane protein undergoes enthalpy- and entropy-driven transitions

Cheneke, B. R., Indic, M., Van Den Berg, B. & Movileanu, L., Jul 3 2012, In : Biochemistry. 51, 26, p. 5348-5358 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Cation selectivity is a conserved feature in the OccD subfamily of Pseudomonas aeruginosa

Liu, J., Wolfe, A. J., Eren, E., Vijayaraghavan, J., Indic, M., Van Den Berg, B. & Movileanu, L., Nov 1 2012, In : Biochimica et Biophysica Acta - Biomembranes. 1818, 11, p. 2908-2916 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Engineering a rigid protein tunnel for biomolecular detection

Mohammad, M. M., Iyer, R., Howard, K. R., McPike, M. P., Borer, P. N. & Movileanu, L., Jun 6 2012, In : Journal of the American Chemical Society. 134, 22, p. 9521-9531 11 p.

Research output: Contribution to journalArticle

78 Scopus citations

Inspection of the Engineered FhuA Δc/Δ4L Protein Nanopore by Polymer Exclusion

Niedzwiecki, D. J., Mohammad, M. M. & Movileanu, L., Nov 21 2012, In : Biophysical Journal. 103, 10, p. 2115-2124 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

OccK channels from pseudomonas aeruginosa exhibit diverse single-channel electrical signatures but conserved anion selectivity

Liu, J., Eren, E., Vijayaraghavan, J., Cheneke, B. R., Indic, M., Van Den Berg, B. & Movileanu, L., Mar 20 2012, In : Biochemistry. 51, 11, p. 2319-2330 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Substrate specificity within a family of outer membrane carboxylate channels

Eren, E., Vijayaraghavan, J., Liu, J., Cheneke, B. R., Touw, D. S., Lepore, B. W., Indic, M., Movileanu, L. & van den Berg, B., Jan 1 2012, In : PLoS Biology. 10, 1, e1001242.

Research output: Contribution to journalArticle

71 Scopus citations
2011

Analysis of gating transitions among the three major open states of the OpdK channel

Cheneke, B. R., Van Den Berg, B. & Movileanu, L., Jun 7 2011, In : Biochemistry. 50, 22, p. 4987-4997 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Monitoring protein adsorption with solid-state nanopores

Niedzwiecki, D. J. & Movileanu, L., Jan 1 2011, In : Journal of Visualized Experiments. 58, e3560.

Research output: Contribution to journalArticle

4 Scopus citations

Redesign of a plugged β-barrel membrane protein

Mohammad, M. M., Howard, K. R. & Movileanu, L., Mar 11 2011, In : Journal of Biological Chemistry. 286, 10, p. 8000-8013 14 p.

Research output: Contribution to journalArticle

43 Scopus citations
2010

Facilitated translocation of polypeptides through a single nanopore

Bikwemu, R., Wolfe, A. J., Xing, X. & Movileanu, L., Nov 17 2010, In : Journal of Physics Condensed Matter. 22, 45, 454117.

Research output: Contribution to journalArticle

36 Scopus citations

Impact of distant charge reversals within a robust β-barrel protein pore

Mohammad, M. M. & Movileanu, L., Jul 8 2010, In : Journal of Physical Chemistry B. 114, 26, p. 8750-8759 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Single-molecule observation of protein adsorption onto an inorganic surface

Niedzwiecki, D. J., Grazul, J. & Movileanu, L., Aug 11 2010, In : Journal of the American Chemical Society. 132, 31, p. 10816-10822 7 p.

Research output: Contribution to journalArticle

85 Scopus citations
2008

Controlling a single protein in a nanopore through electrostatic traps

Mohammad, M. M., Prakash, S., Matouschek, A. & Movileanu, L., Mar 26 2008, In : Journal of the American Chemical Society. 130, 12, p. 4081-4088 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

Crystal Structure of the Outer Membrane Protein OpdK from Pseudomonas aeruginosa

Biswas, S., Mohammad, M. M., Movileanu, L. & van den Berg, B., Jul 9 2008, In : Structure. 16, 7, p. 1027-1035 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Excursion of a single polypeptide into a protein pore: Simple physics, but complicated biology

Mohammad, M. M. & Movileanu, L., Jul 1 2008, In : European Biophysics Journal. 37, 6, p. 913-925 13 p.

Research output: Contribution to journalArticle

57 Scopus citations

Squeezing a single polypeptide through a nanopore

Movileanu, L., Apr 22 2008, In : Soft Matter. 4, 5, p. 925-931 7 p.

Research output: Contribution to journalArticle

68 Scopus citations

Transport at the nanoscale: Temperature dependence of ion conductance

Chimerel, C., Movileanu, L., Pezeshki, S., Winterhalter, M. & Kleinekathöfer, U., Nov 1 2008, In : European Biophysics Journal. 38, 1, p. 121-125 5 p.

Research output: Contribution to journalArticle

55 Scopus citations
2007

Catalyzing the translocation of polypeptides through attractive interactions

Wolfe, A. J., Mohammad, M. M., Cheley, S., Bayley, H. & Movileanu, L., Nov 14 2007, In : Journal of the American Chemical Society. 129, 45, p. 14034-14041 8 p.

Research output: Contribution to journalArticle

111 Scopus citations

Single-molecule electrophoresis of β-hairpin peptides by electrical recordings and Langevin dynamics simulations

Goodrich, C. P., Kirmizialtin, S., Huyghues-Despointes, B. M., Zhu, A., Scholtz, J. M., Makarov, D. E. & Movileanu, L., Apr 5 2007, In : Journal of Physical Chemistry B. 111, 13, p. 3332-3335 4 p.

Research output: Contribution to journalArticle

73 Scopus citations

Structural insight into OprD substrate specificity

Biswas, S., Mohammad, M. M., Patel, D. R., Movileanu, L. & Van Den Berg, B., Nov 1 2007, In : Nature Structural and Molecular Biology. 14, 11, p. 1108-1109 2 p.

Research output: Contribution to journalArticle

68 Scopus citations
2006

Ethanol-induced alterations of the antioxidant defense system in rat kidney

Dinu, D., Nechifor, M. T. & Movileanu, L., Jan 1 2006, In : Journal of Biochemical and Molecular Toxicology. 19, 6, p. 386-395 10 p.

Research output: Contribution to journalArticle

46 Scopus citations

Temperature-responsive protein pores

Jung, Y., Bayley, H. & Movileanu, L., Nov 29 2006, In : Journal of the American Chemical Society. 128, 47, p. 15332-15340 9 p.

Research output: Contribution to journalArticle

94 Scopus citations

Transbilayer pores induced by thickness fluctuations

Movileanu, L., Popescu, D., Ion, S. & Popescu, A. I., Aug 1 2006, In : Bulletin of Mathematical Biology. 68, 6, p. 1231-1255 25 p.

Research output: Contribution to journalArticle

16 Scopus citations
2005

Interactions of peptides with a protein pore

Movileanu, L., Schmittschmitt, J. P., Scholtz, J. M. & Bayley, H., Aug 2005, In : Biophysical Journal. 89, 2, p. 1030-1045 16 p.

Research output: Contribution to journalArticle

200 Scopus citations
2003

Partitioning of individual flexible polymers into a nanoscopic protein pore

Movileanu, L., Cheley, S. & Bayley, H., Aug 1 2003, In : Biophysical Journal. 85, 2, p. 897-910 14 p.

Research output: Contribution to journalArticle

Open Access
86 Scopus citations
2002

Comparative study of some energetic and steric parameters of the wild type and mutants HIV-1 protease: A way to explain the viral resistance

Avram, S., Movileanu, L., Mihailescu, D. & Flonta, M. L., Jan 1 2002, In : Journal of Cellular and Molecular Medicine. 6, 2, p. 251-260 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Determination of base and backbone contributions to the thermodynamics of premelting and melting transitions in B DNA

Movileanu, L., Benevides, J. M. & Thomas, G. J., Sep 1 2002, In : Nucleic acids research. 30, 17, p. 3767-3777 11 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Subunit composition of a bicomponent toxin: Staphylococcal leukocidin forms an octameric transmembrane pore

Miles, G., Movileanu, L. & Bayley, H., Apr 3 2002, In : Protein Science. 11, 4, p. 894-902 9 p.

Research output: Contribution to journalArticle

98 Scopus citations
74 Scopus citations