Jessica MacDonald

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3 Similar Profiles

Corpus Callosum Medicine & Life Sciences

Neurons Medicine & Life Sciences

Olfactory Receptor Neurons Medicine & Life Sciences

Rett Syndrome Medicine & Life Sciences

Histone Deacetylases Medicine & Life Sciences

DNA Methylation Medicine & Life Sciences

Nervous System Medicine & Life Sciences

Phenotype Medicine & Life Sciences

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Projects 2019 2024

2 Active

Restoration of Homeostasis of Downstream Targets of MeCP2 as a Potential Therapeutic for Rett Syndrome

MacDonald, J.

Rettsyndrome.org

4/1/19 → 3/31/21

Project: Research project

Restoration of Homeostasis of Downstream Targets of MeCP2 as a Potential Therapeutic Avenue for Rett Syndrome

MacDonald, J.

National Institute of Neurological Disorders and Stroke/NIH/DHHS

3/1/19 → 1/31/24

Project: Research project

Research Output 2004 2020

792 Citations
9 h-Index
11 Article
1 Chapter
1 Review article

Sex differences in Mecp2-mutant Rett syndrome model mice and the impact of cellular mosaicism in phenotype development

Ribeiro, M. C. & MacDonald, J. L., Feb 15 2020, In : Brain Research. 1729, 146644.

Research output: Contribution to journal › Review article

Rett Syndrome

Mosaicism

Sex Characteristics

Phenotype

X Chromosome Inactivation

4 Citations (Scopus)

Caveolin1 identifies a specific subpopulation of cerebral cortex callosal projection neurons (CPN) including dual projecting cortical callosal/frontal projection neurons (CPN/FPN)

MacDonald, J., Fame, R. M., Gillis-Buck, E. M. & Macklis, J. D., Jan 1 2018, In : eNeuro. 5, 1, e0234-17.2017.

Research output: Contribution to journal › Article

Corpus Callosum

Cerebral Cortex

Neurons

Caveolin 1

Motor Cortex

7 Citations (Scopus)

Cited2 regulates neocortical layer II/III generation and somatosensory callosal projection neuron development and connectivity

Fame, R. M., MacDonald, J., Dunwoodie, S. L., Takahashi, E. & Macklis, J. D., Jun 15 2016, In : Journal of Neuroscience. 36, 24, p. 6403-6419 17 p.

Research output: Contribution to journal › Article

Corpus Callosum

Neurons

Cognition

Somatosensory Cortex

Lateral Ventricles

21 Citations (Scopus)

Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice

Kishi, N., MacDonald, J., Ye, J., Molyneaux, B. J., Azim, E. & Macklis, J. D., Jan 29 2016, In : Nature Communications. 7

Research output: Contribution to journal › Article

Rett Syndrome

phenotype

mice

Corpus Callosum

neurons

6 Citations (Scopus)

Specification of Cortical Projection Neurons: Transcriptional Mechanisms

MacDonald, J., Fame, R. M., Azim, E., Shnider, S. J., Molyneaux, B. J., Arlotta, P. & Macklis, J. D., May 2013, Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing CNS and PNS. Elsevier, p. 475-502 28 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Neurons