• 475 Citations
  • 11 h-Index
20002022
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Fingerprint Dive into the research topics where James L Hougland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Ghrelin Medicine & Life Sciences
Prenylation Medicine & Life Sciences
Acyltransferases Chemical Compounds
Farnesyltranstransferase Medicine & Life Sciences
Substrates Chemical Compounds
Protein Prenylation Medicine & Life Sciences
Dimethylallyltranstransferase Medicine & Life Sciences
Proteins Chemical Compounds

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Projects 2012 2022

Research Output 2000 2019

  • 475 Citations
  • 11 h-Index
  • 29 Article
  • 3 Patent
  • 2 Chapter
  • 2 Review article

Biochemical assays for ghrelin acylation and inhibition of ghrelin O-acyltransferase

Sieburg, M. A., Cleverdon, E. R. & Hougland, J. L., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 227-241 15 p. (Methods in Molecular Biology; vol. 2009).

Research output: Chapter in Book/Report/Conference proceedingChapter

Acyltransferases
Ghrelin
Acylation
Hunger
Inhibition (Psychology)
Acyltransferases
Biochemistry
Ghrelin
Proteins
Endocrinology
9 Citations (Scopus)

Efficient farnesylation of an extended C-terminal C(x)3X sequence motif expands the scope of the prenylated proteome

Blanden, M. J., Suazo, K. F., Hildebrandt, E. R., Hardgrove, D. S., Patel, M., Saunders, W. P., Distefano, M. D., Schmidt, W. K. & Hougland, J. L., Jan 1 2018, In : Journal of Biological Chemistry. 293, 8, p. 2770-2785 16 p.

Research output: Contribution to journalArticle

Farnesyltranstransferase
Prenylation
Proteome
Cysteine
Proteins
2 Citations (Scopus)

Functional group and stereochemical requirements for substrate binding by ghrelin O-acyltransferase revealed by unnatural amino acid incorporation

Cleverdon, E. R., Davis, T. R. & Hougland, J. L., Sep 1 2018, In : Bioorganic Chemistry. 79, p. 98-106 9 p.

Research output: Contribution to journalArticle

Acyltransferases
Ghrelin
Functional groups
Amino Acids
Substrates

Protein isoprenylation in yeast targets COOH-terminal sequences not adhering to the CaaX consensus

Berger, B. M., Kim, J. H., Hildebrandt, E. R., Davis, I. C., Morgan, M. C., Hougland, J. L. & Schmidt, W. K., Dec 1 2018, In : Genetics. 210, 4, p. 1301-1316 16 p.

Research output: Contribution to journalArticle

Protein Prenylation
Prenylation
Yeasts
Dimethylallyltranstransferase
ras Proteins