Projects per year
Fingerprint Dive into the research topics where James L Hougland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Ghrelin
Medicine & Life Sciences
Prenylation
Medicine & Life Sciences
Acyltransferases
Chemical Compounds
Farnesyltranstransferase
Medicine & Life Sciences
Substrates
Chemical Compounds
Protein Prenylation
Medicine & Life Sciences
Dimethylallyltranstransferase
Medicine & Life Sciences
Proteins
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2022
Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase
Hougland, J. L., Nangia, S. & Chisholm, J. D.
National Institutes of Health/DHHS
9/1/19 → 8/31/22
Project: Research project
Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase
Hougland, J. L. & Chisholm, J. D.
National Institutes of Health/DHHS
9/1/19 → 8/31/22
Project: Research project
Minority Undergraduate Internship Award
American Diabetes Association, Inc.
7/1/18 → 6/30/19
Project: Research project
Minority Undergraduate Internship Award
American Diabetes Association, Inc.
9/1/16 → 8/31/17
Project: Research project
Targeting Ghrelin Acylation to Control Glucose Homeostasis
American Diabetes Association, Inc.
1/1/16 → 12/31/16
Project: Research project
Research Output 2000 2019
Biochemical assays for ghrelin acylation and inhibition of ghrelin O-acyltransferase
Sieburg, M. A., Cleverdon, E. R. & Hougland, J. L., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 227-241 15 p. (Methods in Molecular Biology; vol. 2009).Research output: Chapter in Book/Report/Conference proceeding › Chapter
Acyltransferases
Ghrelin
Acylation
Hunger
Inhibition (Psychology)
Ghrelin octanoylation by ghrelin O-acyltransferase: Unique protein biochemistry underlying metabolic signaling
Hougland, J. L., Jan 1 2019, In : Biochemical Society Transactions. 47, 1, p. 169-178 10 p.Research output: Contribution to journal › Review article
Acyltransferases
Biochemistry
Ghrelin
Proteins
Endocrinology
9
Citations
(Scopus)
Efficient farnesylation of an extended C-terminal C(x)3X sequence motif expands the scope of the prenylated proteome
Blanden, M. J., Suazo, K. F., Hildebrandt, E. R., Hardgrove, D. S., Patel, M., Saunders, W. P., Distefano, M. D., Schmidt, W. K. & Hougland, J. L., Jan 1 2018, In : Journal of Biological Chemistry. 293, 8, p. 2770-2785 16 p.Research output: Contribution to journal › Article
Farnesyltranstransferase
Prenylation
Proteome
Cysteine
Proteins
2
Citations
(Scopus)
Functional group and stereochemical requirements for substrate binding by ghrelin O-acyltransferase revealed by unnatural amino acid incorporation
Cleverdon, E. R., Davis, T. R. & Hougland, J. L., Sep 1 2018, In : Bioorganic Chemistry. 79, p. 98-106 9 p.Research output: Contribution to journal › Article
Acyltransferases
Ghrelin
Functional groups
Amino Acids
Substrates
Protein isoprenylation in yeast targets COOH-terminal sequences not adhering to the CaaX consensus
Berger, B. M., Kim, J. H., Hildebrandt, E. R., Davis, I. C., Morgan, M. C., Hougland, J. L. & Schmidt, W. K., Dec 1 2018, In : Genetics. 210, 4, p. 1301-1316 16 p.Research output: Contribution to journal › Article
Protein Prenylation
Prenylation
Yeasts
Dimethylallyltranstransferase
ras Proteins
Press and Media
Weight loss news: This popular oil could be key to combating hunger
7/31/17
1 item of media coverage
Press/Media: Expert Comment
July 28, 2017: Syracuse University: Biochemists Link Synthetic Compound to Hunger-Hormone Production
James L Hougland, Dawn Rene Johnson, Andria Costello Staniec & John D Chisholm
7/28/17
1 item of media coverage
Press/Media: Expert Comment
BIOCHEMISTS LINK SYNTHETIC COMPOUND TO HUNGER-HORMONE PRODUCTION
James L Hougland & John D Chisholm
7/27/17
1 item of media coverage
Press/Media: Expert Comment
US Patent Issued to SYRACUSE UNIVERSITY on May 17 for "Inhibitors targeting human ghrelin O-acyltransferase" (New York Inventor)
5/19/16
1 item of media coverage
Press/Media: Expert Comment