Projects per year
Personal profile
Research Interests
- protein biochemistry
- post translational modification
- protein acylation
- ghrelin
- metabolic disease
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Dive into the research topics where James L Hougland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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REU Site: Undergraduate Research in Chemistry at Syracuse University
Sponsler, M. & Hougland, J. L.
4/1/20 → 3/31/24
Project: Sponsored Project
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Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase Equipment Supplement
9/1/19 → 8/31/23
Project: Sponsored Project
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Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase
9/1/19 → 8/31/23
Project: Sponsored Project
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Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase
Hougland, J. L. & Chisholm, J. D.
9/1/19 → 8/31/23
Project: Sponsored Project
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A rising tide lifts all MBOATs: recent progress in structural and functional understanding of membrane bound O-acyltransferases
Pierce, M. R. & Hougland, J. L., 2023, In: Frontiers in Physiology. 14, 1167873.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Cellular Uptake of a Fluorescent Ligand Reveals Ghrelin O-Acyltransferase Interacts with Extracellular Peptides and Exhibits Unexpected Localization for a Secretory Pathway Enzyme
Campaña, M. B., Davis, T. R., Novak, S. X., Cleverdon, E. R., Bates, M., Krishnan, N., Curtis, E. R., Childs, M. D., Pierce, M. R., Morales-Rodriguez, Y., Sieburg, M. A., Hehnly, H., Luyt, L. G. & Hougland, J. L., Aug 18 2023, In: ACS Chemical Biology. 18, 8, p. 1880-1890 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Initial Pharmacological Characterization of a Major Hydroxy Metabolite of PF-5190457: Inverse Agonist Activity of PF-6870961 at the Ghrelin Receptor
Deschaine, S. L., Hedegaard, M. A., Pince, C. L., Farokhnia, M., Moose, J. E., Stock, I. A., Adusumalli, S., Akhlaghi, F., Hougland, J. L., Sulima, A., Rice, K. C., Koob, G. F., Vendruscolo, L. F., Holst, B. & Leggio, L., Aug 1 2023, In: Journal of Pharmacology and Experimental Therapeutics. 386, 2, p. 117-128 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A closer look at alcohol-induced changes in the ghrelin system: novel insights from preclinical and clinical data
Deschaine, S. L., Farokhnia, M., Gregory-Flores, A., Zallar, L. J., You, Z. B., Sun, H., Harvey, D. M., Marchette, R. C. N., Tunstall, B. J., Mani, B. K., Moose, J. E., Lee, M. R., Gardner, E., Akhlaghi, F., Roberto, M., Hougland, J. L., Zigman, J. M., Koob, G. F., Vendruscolo, L. F. & Leggio, L., Jan 2022, In: Addiction Biology. 27, 1, e13033.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation
Morstein, J., Bader, T., Cardillo, A. L., Schackmann, J., Ashok, S., Hougland, J. L., Hrycyna, C. A., Trauner, D. H. & Distefano, M. D., Oct 21 2022, In: ACS Chemical Biology. 17, 10, p. 2945-2953 9 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Press and Media
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Researchers from Syracuse University Discuss Findings in Physiology (A rising tide lifts all MBOATs: recent progress in structural and functional understanding of membrane bound O-acyltransferases)
5/24/23
1 item of Media coverage
Press/Media: Expert Comment