James L Hougland

Accepting PhD Students

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Research activity per year

Research Interests

protein biochemistry
post translational modification
protein acylation
ghrelin
metabolic disease

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Dive into the research topics where James L Hougland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

1 Similar Profiles

14 Finished

REU Site: Undergraduate Research in Chemistry at Syracuse University
Sponsler, M. (PI) & Hougland, J. L. (CoI)
4/1/20 → 3/31/24
Project: Sponsored Project
Determining the Scope of Prenylatable Protein Sequences
Hougland, J. L. (PI)
9/20/19 → 7/31/23
Project: Sponsored Project
Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase
Hougland, J. L. (PI)
9/1/19 → 8/31/23
Project: Sponsored Project
Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase Equipment Supplement
Hougland, J. L. (PI)
9/1/19 → 8/31/23
Project: Sponsored Project
Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase
Hougland, J. L. (PI) & Chisholm, J. D. (CoI)
9/1/19 → 8/31/23
Project: Sponsored Project

40 Article
6 Review article
5 Patent
3 Chapter
More
- 1 Short Survey Article

Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase
Schey, G. L., Hildebrandt, E. R., Wang, Y., Diwan, S., Passetti, H. A., Potts, G. W., Sprague-Getsy, A. M., Leoni, E. R., Kuebler, T. S., Sham, Y. Y., Hougland, J. L., Beese, L. S., Schmidt, W. K. & Distefano, M. D., May 2024, In: International journal of molecular sciences. 25, 10, 5324.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Targeted genetic and small molecule disruption of N-Ras CaaX cleavage alters its localization and oncogenic potential
Hildebrandt, E. R., Hussain, S. A., Sieburg, M. A., Ravishankar, R., Asad, N., Gore, S., Ito, T., Hougland, J. L., Dore, T. M. & Schmidt, W. K., Jun 2024, In: Bioorganic Chemistry. 147, 107316.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
A rising tide lifts all MBOATs: recent progress in structural and functional understanding of membrane bound O-acyltransferases
Pierce, M. R. & Hougland, J. L., 2023, In: Frontiers in Physiology. 14, 1167873.
Research output: Contribution to journal › Review article › peer-review

Open Access
7 Scopus citations
Cellular Uptake of a Fluorescent Ligand Reveals Ghrelin O-Acyltransferase Interacts with Extracellular Peptides and Exhibits Unexpected Localization for a Secretory Pathway Enzyme
Campaña, M. B., Davis, T. R., Novak, S. X., Cleverdon, E. R., Bates, M., Krishnan, N., Curtis, E. R., Childs, M. D., Pierce, M. R., Morales-Rodriguez, Y., Sieburg, M. A., Hehnly, H., Luyt, L. G. & Hougland, J. L., Aug 18 2023, In: ACS Chemical Biology. 18, 8, p. 1880-1890 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Combined Computational-Biochemical Approach Offers an Accelerated Path to Membrane Protein Solubilization
Pierce, M. R., Ji, J., Novak, S. X., Sieburg, M. A., Nangia, S., Nangia, S. & Hougland, J. L., Nov 27 2023, In: Journal of Chemical Information and Modeling. 63, 22, p. 7159-7170 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access

Microfluidics could enable rapid at-home testing for common STIs
Hougland, J. L.
8/20/24
1 item of Media coverage
Press/Media: Expert Comment
Syracuse University Reports Findings in Membrane Proteins (Combined Computational-Biochemical Approach Offers an Accelerated Path to Membrane Protein Solubilization)
Nangia, S. & Hougland, J. L.
11/22/23
1 item of Media coverage
Press/Media: Expert Comment
Researchers from Syracuse University Discuss Findings in Physiology (A rising tide lifts all MBOATs: recent progress in structural and functional understanding of membrane bound O-acyltransferases)
Hougland, J. L.
5/24/23
1 item of Media coverage
Press/Media: Expert Comment

James L Hougland

Personal profile

Research Interests

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

REU Site: Undergraduate Research in Chemistry at Syracuse University

Determining the Scope of Prenylatable Protein Sequences

Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase

Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase Equipment Supplement

Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase

Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase

Targeted genetic and small molecule disruption of N-Ras CaaX cleavage alters its localization and oncogenic potential

A rising tide lifts all MBOATs: recent progress in structural and functional understanding of membrane bound O-acyltransferases

Cellular Uptake of a Fluorescent Ligand Reveals Ghrelin O-Acyltransferase Interacts with Extracellular Peptides and Exhibits Unexpected Localization for a Secretory Pathway Enzyme

Combined Computational-Biochemical Approach Offers an Accelerated Path to Membrane Protein Solubilization

Microfluidics could enable rapid at-home testing for common STIs

Syracuse University Reports Findings in Membrane Proteins (Combined Computational-Biochemical Approach Offers an Accelerated Path to Membrane Protein Solubilization)

Researchers from Syracuse University Discuss Findings in Physiology (A rising tide lifts all MBOATs: recent progress in structural and functional understanding of membrane bound O-acyltransferases)

James L Hougland

Personal profile

Research Interests

Fingerprint

Collaborations and top research areas from the last five years

Projects

Research output

Press and Media