• 506 Citations
  • 12 h-Index
20002022
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Fingerprint Dive into the research topics where James L Hougland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Ghrelin Medicine & Life Sciences
Acyltransferases Chemical Compounds
Prenylation Medicine & Life Sciences
Farnesyltranstransferase Medicine & Life Sciences
Substrates Chemical Compounds
Protein Prenylation Medicine & Life Sciences
Acylation Medicine & Life Sciences
Proteins Chemical Compounds

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Projects 2012 2022

Research Output 2000 2019

  • 506 Citations
  • 12 h-Index
  • 30 Article
  • 3 Review article
  • 3 Patent
  • 2 Chapter
2 Citations (Scopus)

Biochemical assays for ghrelin acylation and inhibition of ghrelin O-acyltransferase

Sieburg, M. A., Cleverdon, E. R. & Hougland, J. L., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 227-241 15 p. (Methods in Molecular Biology; vol. 2009).

Research output: Chapter in Book/Report/Conference proceedingChapter

Acyltransferases
Ghrelin
Acylation
Hunger
Inhibition (Psychology)
3 Citations (Scopus)
Acyltransferases
Biochemistry
Ghrelin
Proteins
Endocrinology

Ghrelin Signaling: GOAT and GHS-R1a Take a LEAP in Complexity

Abizaid, A. & Hougland, J. L., Jan 1 2019, (Accepted/In press) In : Trends in Endocrinology and Metabolism.

Research output: Contribution to journalReview article

Ghrelin Receptor
Ghrelin
Obesity
Cachexia
Appetite
3 Citations (Scopus)

The ghrelin O-acyltransferase structure reveals a catalytic channel for transmembrane hormone acylation

Campaña, M. B., Irudayanathan, F. J., Davis, T. R., McGovern-Gooch, K. R., Loftus, R., Ashkar, M., Escoffery, N., Navarro, M., Sieburg, M. A., Nangia, S. & Hougland, J. L., Jan 1 2019, In : Journal of Biological Chemistry. 294, 39, p. 14166-14174 9 p.

Research output: Contribution to journalArticle

Cytology
Acyltransferases
Acylation
Ghrelin
Hormones
9 Citations (Scopus)

Efficient farnesylation of an extended C-terminal C(x)3X sequence motif expands the scope of the prenylated proteome

Blanden, M. J., Suazo, K. F., Hildebrandt, E. R., Hardgrove, D. S., Patel, M., Saunders, W. P., Distefano, M. D., Schmidt, W. K. & Hougland, J. L., Jan 1 2018, In : Journal of Biological Chemistry. 293, 8, p. 2770-2785 16 p.

Research output: Contribution to journalArticle

Farnesyltranstransferase
Prenylation
Proteome
Cysteine
Proteins