Projects per year
Personal profile
Research Interests
- protein biochemistry
- post translational modification
- protein acylation
- ghrelin
- metabolic disease
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Dive into the research topics where James L Hougland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
- 14 Finished
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REU Site: Undergraduate Research in Chemistry at Syracuse University
Sponsler, M. (PI) & Hougland, J. L. (CoI)
4/1/20 → 3/31/24
Project: Sponsored Project
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Determining the Scope of Prenylatable Protein Sequences
Hougland, J. L. (PI)
9/20/19 → 7/31/23
Project: Sponsored Project
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Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase
Hougland, J. L. (PI)
9/1/19 → 8/31/23
Project: Sponsored Project
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Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase Equipment Supplement
Hougland, J. L. (PI)
9/1/19 → 8/31/23
Project: Sponsored Project
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Defining the Molecular Architecture for Transmembrane Acylation by a Membrane Bound O-Acyltransferase
Hougland, J. L. (PI) & Chisholm, J. D. (CoI)
9/1/19 → 8/31/23
Project: Sponsored Project
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An Alkyne-Containing Isoprenoid Analogue Based on a Farnesyl Diphosphate Scaffold Is a Biologically Functional Universal Probe for Proteomic Analysis
Auger, S. A., Pedersen, J. S., Maity, S., Sprague-Getsy, A. M., Lorimer, E. L., Koehn, O. J., Krauklis, S. A., Berns, B., Murphy, K. M., Hussain, J., Thao, P., Bernhagen, K., Justyna, K., Sundaresan, A. P., McKim, D. B., Williams, C. L., Hougland, J. L., Li, L. & Distefano, M. D., 2024, (Accepted/In press) In: Biochemistry.Research output: Contribution to journal › Article › peer-review
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Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase
Schey, G. L., Hildebrandt, E. R., Wang, Y., Diwan, S., Passetti, H. A., Potts, G. W., Sprague-Getsy, A. M., Leoni, E. R., Kuebler, T. S., Sham, Y. Y., Hougland, J. L., Beese, L. S., Schmidt, W. K. & Distefano, M. D., May 2024, In: International journal of molecular sciences. 25, 10, 5324.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeted genetic and small molecule disruption of N-Ras CaaX cleavage alters its localization and oncogenic potential
Hildebrandt, E. R., Hussain, S. A., Sieburg, M. A., Ravishankar, R., Asad, N., Gore, S., Ito, T., Hougland, J. L., Dore, T. M. & Schmidt, W. K., Jun 2024, In: Bioorganic Chemistry. 147, 107316.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A rising tide lifts all MBOATs: recent progress in structural and functional understanding of membrane bound O-acyltransferases
Pierce, M. R. & Hougland, J. L., 2023, In: Frontiers in Physiology. 14, 1167873.Research output: Contribution to journal › Review article › peer-review
Open Access8 Scopus citations -
Cellular Uptake of a Fluorescent Ligand Reveals Ghrelin O-Acyltransferase Interacts with Extracellular Peptides and Exhibits Unexpected Localization for a Secretory Pathway Enzyme
Campaña, M. B., Davis, T. R., Novak, S. X., Cleverdon, E. R., Bates, M., Krishnan, N., Curtis, E. R., Childs, M. D., Pierce, M. R., Morales-Rodriguez, Y., Sieburg, M. A., Hehnly, H., Luyt, L. G. & Hougland, J. L., Aug 18 2023, In: ACS Chemical Biology. 18, 8, p. 1880-1890 11 p.Research output: Contribution to journal › Article › peer-review
Open Access
Press and Media
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Research Distinction Awards Presented at BioInspired Symposium
Soman, P., Hougland, J. L., Movileanu, L., Mozhdehi, D., Shan, W. & Hu, X.
10/31/24
1 item of Media coverage
Press/Media: Expert Comment
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Research Distinction Awards Presented at BioInspired Symposium
Soman, P., Hougland, J. L., Movileanu, L., Mozhdehi, D., Shan, W. & Hu, X.
10/31/24
1 item of Media coverage
Press/Media: Expert Comment
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RESEARCH DISTINCTION AWARDS PRESENTED AT BIOINSPIRED SYMPOSIUM
Soman, P., Hougland, J. L., Movileanu, L., Mozhdehi, D. & Shan, W.
10/31/24
1 item of Media coverage
Press/Media: Expert Comment
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Microfluidics could enable rapid at-home testing for common STIs
8/20/24
1 item of Media coverage
Press/Media: Expert Comment
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Syracuse University Reports Findings in Membrane Proteins (Combined Computational-Biochemical Approach Offers an Accelerated Path to Membrane Protein Solubilization)
11/22/23
1 item of Media coverage
Press/Media: Expert Comment